{"id":1192,"date":"2025-12-21T08:25:02","date_gmt":"2025-12-21T08:25:02","guid":{"rendered":"http:\/\/60.204.213.123\/?page_id=1192"},"modified":"2026-02-03T10:06:48","modified_gmt":"2026-02-03T10:06:48","slug":"%e5%be%ae%e9%87%8fpmhc%e5%a4%8d%e5%90%88%e7%89%a9%e5%90%88%e6%88%90","status":"publish","type":"page","link":"https:\/\/www.guixiong.com.cn\/?page_id=1192","title":{"rendered":"\u5fae\u91cfpMHC\u590d\u5408\u7269\u5408\u6210"},"content":{"rendered":"\r\n<h3 class=\"wp-block-heading has-text-align-center has-secondary-color has-primary-light-background-color has-text-color has-background has-link-color wp-elements-27f50c059c4c1b62b902d0d79c1a261d\">\u670d\u52a1\u4ef7\u503c<\/h3>\r\n\r\n\r\n\r\n<h4 class=\"wp-block-heading\">\u6297\u539f\u7b5b\u9009<\/h4>\r\n\r\n\r\n\r\n<p>\u7531\u4e8e\u6297\u539f\u80bd\u548cMHC\u5b58\u5728\u4e0d\u7ed3\u5408\u7684\u53ef\u80fd\uff0c\u4ece\u800c\u5bfc\u81f4\u590d\u5408\u7269\u65e0\u6cd5\u751f\u6210\uff0c\u56e0\u6b64\u6839\u636e\u5408\u6210\u4ea7\u7269\u662f\u5426\u751f\u6210\u5224\u65ad\u6297\u539f\u80bd\u662f\u5426\u7ed3\u5408MHC\uff0c\u4ece\u800c\u5b9e\u73b0\u6297\u539f\u7b5b\u9009\u7684\u4f5c\u7528\u3002\u672c\u670d\u52a1\u63d0\u4f9b\u5408\u6210\u540e\u4ea7\u7269\u6d53\u5ea6\u5206\u6790\uff0c\u5b9e\u73b0\u6297\u539f\u7b5b\u9009\u4ef7\u503c\uff1b<\/p>\r\n\r\n\r\n\r\n<h4 class=\"wp-block-heading\">\u5e72\u51c0\u7684\u80cc\u666f<\/h4>\r\n\r\n\r\n\r\n<p>\u672c\u670d\u52a1\u4e0d\u4f7f\u7528\u7f6e\u6362\u80bd\u5de5\u827a\uff0c\u65e0\u5e72\u6270\u6297\u539f\u6df7\u6742\uff0c\u4e0d\u5e72\u6270\u4e0b\u6e38\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u68c0\u6d4b\u3001TCR\u7ec4\u5e93\u5206\u6790\u3001\u6548\u5e94TCR\u7b5b\u9009\u3002<\/p>\r\n\r\n\r\n\r\n<h4 class=\"wp-block-heading\">\u7075\u6d3b\u7684\u4e0b\u6e38\u5e94\u7528<\/h4>\r\n\r\n\r\n\r\n<p>\u5fae\u91cfpMHC\u590d\u5408\u7269\u542b\u751f\u7269\u7d20\u6807\u8bb0\uff0c\u4e3a\u7528\u6237\u63d0\u4f9b\u4e0b\u6e38\u5de5\u4f5c\u63d0\u4f9b\u4e86\u6807\u51c6\u63a5\u53e3\u3002\u7528\u6237\u53ef\u7075\u6d3b\u7ed3\u5408\u4efb\u4f55\u643a\u5e26\u94fe\u9709\u4eb2\u548c\u7d20\u7684\u62a5\u544a\u5206\u5b50\uff0c\u6bd4\u5982\uff1a<\/p>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n<li style=\"line-height: 2;\"><span style=\"font-size: revert;\">\u94fe\u9709\u4eb2\u548c\u7d20-\u8367\u5149\u5206\u5b50\uff1a\u7528\u4e8e\u6d41\u5f0f\u5206\u6790\u3001\u5206\u9009\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\uff1b<\/span><\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\">\u94fe\u9709\u4eb2\u548c\u7d20-\u78c1\u73e0\uff1a\u7528\u4e8e\u78c1\u73e0\u5206\u9009\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\uff1b<\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\">DNA-barcode\u6807\u8bb0\uff1a\u5bf9\u4e8e\u5355\u4e2a\u5f85\u6d4bPBMC\u6837\u672c(\u6216\u57f9\u517b\u7684T\u7ec6\u80de)\uff0c\u53ef\u5b9e\u73b0\u6700\u9ad83000\u79cd\u6297\u539f\u7684<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=136\" data-type=\"link\" data-id=\"https:\/\/www.guixiong.com.cn\/?page_id=136\">\u7279\u5f02\u6027T\u7ec6\u80de\u6570\u91cf\u68c0\u6d4b<\/a>\u3001<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=597\" data-type=\"link\" data-id=\"https:\/\/www.guixiong.com.cn\/?page_id=597\">\u7279\u5f02\u6027TCR\u7b5b\u9009(alpha\u94fe\u548cbeta\u94fe\u914d\u5bf9)<\/a><\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\">\u94fe\u9709\u4eb2\u548c\u7d20-\u8fa3\u6839\u8fc7\u6c27\u5316\u7269\u9176\uff1a\u7528\u4e8e\u514d\u75ab\u7ec4\u5316\u6216\u514d\u75ab\u7ec6\u80de\u5316\u5b66\u6807\u8bb0\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u3002<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<h3 class=\"wp-block-heading has-text-align-center has-primary-light-background-color has-background\">\u751f\u4ea7\u5468\u671f<\/h3>\r\n\r\n\r\n\r\n<h4 class=\"wp-block-heading\">\u5feb\u901f\u5468\u671f<\/h4>\r\n\r\n\r\n\r\n<p>\u5ba2\u6237\u591a\u80bd\u5230\u8fbe\u540e\uff0c\u7b26\u5408\u5982\u4e0b\u6761\u4ef6\u751f\u4ea7\u5468\u671f\u4e3a1\u5468\uff1a<\/p>\r\n\r\n\r\n\r\n<ul class=\"wp-block-list\">\r\n<li style=\"line-height: 2;\"><span style=\"font-size: revert;\">HLA-A\u7c7b\u578b\uff1a A*02:01\u3001A*11:01\u3001A*24:02\u3001A*33:01\u3001A*31:01<\/span><\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\"><span style=\"font-size: revert;\">HLA-B\u7c7b\u578b\uff1aB*15:01\u3001B*15:02\u3001B*40:01<\/span><\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\"><span style=\"font-size: revert;\">HLA-C\u7c7b\u578b\uff1aC*01:02\u3001C*03:04\u3001C*07:02<\/span><\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\"><span style=\"font-size: revert;\">HLA-DRB1\u7c7b\u578b\uff1aHLA-DRB1*01:01\/ DRA1*01:01\u3001HLA-DRB1*04:01\/ DRA1*01:01\u3001HLA-DRB1*04:05\/ DRA1*01:01\u3001HLA-DRB1*15:01\/ DRA1*01:01<\/span><\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\"><span style=\"font-size: revert;\">HLA-DPB1\u7c7b\u578b\uff1aHLA-DPB1*02:01\/DPA1*01:03<\/span><\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\">\u5c0f\u9f20MHC\u7c7b\u578b\uff1aH2Kb\u3001H2Kd\u3001H2Ld\u3001H2Db\u3001H2-IA\u3001H2-IE<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n<h4 class=\"wp-block-heading\">\u6807\u51c6\u5468\u671f<\/h4>\r\n\r\n\r\n\r\n<p>\u9664\u4e0a\u8ff0MHC\u7c7b\u578b\u5916\uff0c\u5176\u4f59MHC\u7c7b\u578b(MHC-I\u578b\/II\u578b)\u7684pMHC\u590d\u5408\u7269\u751f\u4ea7\u5468\u671f\u4e3a2\u5468<\/p>\r\n\r\n\r\n\r\n<h3 class=\"wp-block-heading has-text-align-center has-primary-light-background-color has-background\">\u4ef7\u683c<\/h3>\r\n\r\n\r\n\r\n<figure class=\"wp-block-table\">\r\n<table>\r\n<tbody>\r\n<tr>\r\n<td>\u89c4\u683c<\/td>\r\n<td>2ug pMHC\u590d\u5408\u7269 \u5355\u4ef7(\u5143)<\/td>\r\n<td>5ug pMHC\u590d\u5408\u7269\u5355\u4ef7(\u5143)<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u65e0\u4fee\u9970<\/td>\r\n<td>560<\/td>\r\n<td>920<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u53e6\u52a0PE\u8367\u5149\u6216APC\u8367\u5149<\/td>\r\n<td>60<\/td>\r\n<td>100<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u53e6\u52a0\u78c1\u73e0\u6807\u8bb0<\/td>\r\n<td>100<\/td>\r\n<td>180<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u53e6\u52a0DNA barcode\u6807\u8bb0<\/td>\r\n<td>230<\/td>\r\n<td>430<\/td>\r\n<\/tr>\r\n<tr>\r\n<td>\u53e6\u52a0\u94fe\u9709\u4eb2\u548c\u7d20-\u8fa3\u6839\u8fc7\u6c27\u5316\u7269\u9176<\/td>\r\n<td>42<\/td>\r\n<td>70<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/figure>\r\n\r\n\r\n\r\n<p>\u7279\u522b\u8bf4\u660e\uff1a<\/p>\r\n\r\n\r\n\r\n<ol class=\"wp-block-list\">\r\n<li style=\"line-height: 2;\">\u4ee5\u6807\u51c6\u9633\u6027\u6297\u539f\u80bdCMV pp65 \u523a\u6fc01ml HLA-A*02:01\u5065\u5eb7\u5fd7\u613f\u8005PBMC\u540e\u4ea7\u751f\u7684\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u6570\u91cf\u8ba1\uff0c1ug pMHC\u590d\u5408\u7269\u6807\u8bb0\u8367\u5149\u540e\u53ef\u68c0\u6d4b\u51fa\u7684CMV pp65\u7279\u5f02\u6027CD8+ T\u7ec6\u80de\u4ea7\u751f\u7ea6\u5360\u6bd42%\u3002<\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\">\u65e0\u8d77\u8ba2\u91cf\u8981\u6c42\uff0c1\u4e2a\u591a\u80bd\u5373\u53ef\u8d77\u8ba2\u3002<\/li>\r\n\r\n\r\n\r\n<li style=\"line-height: 2;\">\u65e0\u591a\u80bd\u6570\u91cf\u4e0a\u9650\u3002<\/li>\r\n<\/ol>\r\n<p>Views: 56<\/p>","protected":false},"excerpt":{"rendered":"<p>\u670d\u52a1\u4ef7\u503c \u6297\u539f\u7b5b\u9009 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