{"id":1620,"date":"2026-01-28T07:47:49","date_gmt":"2026-01-28T07:47:49","guid":{"rendered":"https:\/\/www.guixiong.com.cn\/?page_id=1620"},"modified":"2026-01-28T14:05:22","modified_gmt":"2026-01-28T14:05:22","slug":"%e5%85%8d%e7%96%ab%e7%95%8c%e7%9a%84%e5%85%a8%e8%83%bd%e6%8c%87%e6%8c%a5%e5%ae%98%ef%bc%9a%e6%a0%91%e7%aa%81%e7%8a%b6%e7%bb%86%e8%83%9e%e5%a6%82%e4%bd%95%e6%94%b9%e5%86%99%e7%96%be","status":"publish","type":"page","link":"https:\/\/www.guixiong.com.cn\/?page_id=1620","title":{"rendered":"\u514d\u75ab\u754c\u7684\u201c\u5168\u80fd\u6307\u6325\u5b98\u201d\uff1a\u6811\u7a81\u72b6\u7ec6\u80de\u5982\u4f55\u6539\u5199\u75be\u75c5\u6cbb\u7597\u683c\u5c40\uff1f"},"content":{"rendered":"<p data-pm-slice=\"2 2 []\">\ud83d\udca1 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class=\"list-paddingleft-1\">\n<li><strong>cDC1s\uff1a\u64c5\u957f\u4ea4\u53c9\u63d0\u5448\u80bf\u7624\u6297\u539f\uff0c\u6fc0\u6d3b\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\uff1b<\/strong><\/li>\n<li><strong>pDCs\uff1a\u5927\u91cf\u5206\u6cccI\u578b\u5e72\u6270\u7d20\uff0c\u5728\u6297\u75c5\u6bd2\u4e2d\u53d1\u6325\u5173\u952e\u4f5c\u7528\uff1b<\/strong><\/li>\n<li><strong>LCs\uff1a\u575a\u5b88\u76ae\u80a4\u7b49\u4e0a\u76ae\u7ec4\u7ec7\uff0c\u6784\u6210\u514d\u75ab\u7b2c\u4e00\u9053\u9632\u7ebf\u3002<\/strong><\/li>\n<\/ul>\n<h3>\u4e8c\u3001DCs\u7684\u201c\u5168\u80fd\u6280\u80fd\u201d\uff1a\u4ece\u514d\u75ab\u6fc0\u6d3b\u5230\u8010\u53d7\u8c03\u8282<\/h3>\n<h5>\u6297\u539f\u5904\u7406\u4e0e\u63d0\u5448<\/h5>\n<p>DCs\u901a\u8fc7\u5de8\u80de\u996e\u3001\u541e\u566c\u4f5c\u7528\u548c\u53d7\u4f53\u4ecb\u5bfc\u5185\u541e\u7b49\u65b9\u5f0f\u6355\u83b7\u6297\u539f\uff0c\u5c06\u5176\u964d\u89e3\u4e3a\u80bd\u6bb5\u540e\uff0c\u901a\u8fc7MHC\u2160\u7c7b\u5206\u5b50\u63d0\u5448\u7ed9CD8\u207aT\u7ec6\u80de\uff0c\u6216\u901a\u8fc7MHC\u2161\u7c7b\u5206\u5b50\u63d0\u5448\u7ed9CD4\u207aT\u7ec6\u80de\u3002\u5c24\u4e3a\u7279\u6b8a\u7684\u662f\u201c\u4ea4\u53c9\u63d0\u5448\u201d\u80fd\u529b\u2014\u2014cDC1s\u53ef\u5c06\u5916\u6e90\u6027\u6297\u539f\u901a\u8fc7MHC\u2160\u7c7b\u5206\u5b50\u63d0\u5448\uff0c\u6fc0\u6d3b\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\u3002<\/p>\n<h5>\u514d\u75ab\u6fc0\u6d3b<\/h5>\n<p>DCs\u901a\u8fc7\u201c\u4e09\u4fe1\u53f7\u673a\u5236\u201d\u542f\u52a8\u9002\u5e94\u6027\u514d\u75ab\uff1aT\u7ec6\u80de\u53d7\u4f53\u8bc6\u522b\u6297\u539f-MHC\u590d\u5408\u7269\uff08\u7b2c\u4e00\u4fe1\u53f7\uff09\uff0cCD80\/CD86\u4e0eCD28\u7ed3\u5408\u63d0\u4f9b\u5171\u523a\u6fc0\u4fe1\u53f7\uff08\u7b2c\u4e8c\u4fe1\u53f7\uff09\uff0cDCs\u5206\u6cccIL-12\u3001IFN\u7b49\u7ec6\u80de\u56e0\u5b50\u5f15\u5bfcT\u7ec6\u80de\u5206\u5316\uff08\u7b2c\u4e09\u4fe1\u53f7\uff09\u3002\u8fd9\u4e00\u8fc7\u7a0b\u53ef\u6fc0\u6d3bCD4\u207aT\u7ec6\u80de\u5206\u5316\u4e3aTh1\u3001Th2\u3001Th17\u7b49\u6548\u5e94\u4e9a\u7fa4\uff0cCD8\u207aT\u7ec6\u80de\u5206\u5316\u4e3a\u7ec6\u80de\u6bd2\u6027T\u7ec6\u80de\uff0c\u540c\u65f6\u4fc3\u8fdbB\u7ec6\u80de\u4ea7\u751f\u6297\u4f53\u3002<\/p>\n<h5>\u514d\u75ab\u8c03\u8282<\/h5>\n<p>DCs\u4e0d\u4ec5\u80fd\u542f\u52a8\u514d\u75ab\u653b\u51fb\uff0c\u8fd8\u80fd\u901a\u8fc7\u4e2d\u67a2\u8010\u53d7\uff08\u80f8\u817a\u4e2d\u6e05\u9664\u81ea\u8eab\u53cd\u5e94\u6027T\u7ec6\u80de\uff09\u548c\u5916\u5468\u8010\u53d7\uff08\u8bf1\u5bfc\u8c03\u8282\u6027T\u7ec6\u80de\uff09\u907f\u514d\u514d\u75ab\u8fc7\u5ea6\u6fc0\u6d3b\u3002\u5f53\u8f6c\u5316\u4e3atolDCs\u65f6\uff0c\u4f1a\u901a\u8fc7\u5206\u6cccIL-10\u3001TGF-\u03b2\u7b49\u6291\u5236\u6027\u7ec6\u80de\u56e0\u5b50\uff0c\u7ef4\u6301\u673a\u4f53\u514d\u75ab\u5e73\u8861\u3002<\/p>\n<h3>\u00a0\u4e09\u3001\u75be\u75c5\u6cbb\u7597\u7684\u201c\u65b0\u6b66\u5668\u201d\uff1aDCs\u7684\u4e34\u5e8a\u5e94\u7528\u7a81\u7834<\/h3>\n<h5>\uff08\u4e00\uff09\u764c\u75c7\u514d\u75ab\u6cbb\u7597\uff1a\u4ece\u75ab\u82d7\u5230\u8054\u5408\u7597\u6cd5<\/h5>\n<p>DC\u75ab\u82d7\u901a\u8fc7\u52a0\u8f7d\u80bf\u7624\u6297\u539f\uff0c\u6fc0\u6d3b\u673a\u4f53\u81ea\u8eab\u6297\u80bf\u7624\u514d\u75ab\u3002\u9996\u4e2a\u83b7\u6279\u7684\u524d\u5217\u817a\u764c\u75ab\u82d7Provenge\uff08sipuleucel-T\uff09\u53ef\u5ef6\u957f\u60a3\u8005\u4e2d\u4f4d\u751f\u5b58\u671f4.1\u4e2a\u6708\u3002\u5982\u4eca\uff0cDC\u75ab\u82d7\u5df2\u53d1\u5c55\u51fa\u591a\u79cd\u5f62\u5f0f\uff1a\u80bd\u8d1f\u8f7d\u75ab\u82d7\u3001\u57fa\u56e0\u5de5\u7a0b\u75ab\u82d7\u3001\u4e2a\u6027\u5316\u65b0\u6297\u539f\u75ab\u82d7\u7b49\u3002<\/p>\n<ul class=\"list-paddingleft-1\">\n<li>\n<section>\u9ed1\u8272\u7d20\u7624\u3001\u809d\u764c\u3001\u80f0\u817a\u764c\u7b49\u591a\u79cd\u764c\u75c7\u7684\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\uff0cDC\u75ab\u82d7\u80fd\u6709\u6548\u6fc0\u6d3b\u80bf\u7624\u7279\u5f02\u6027T\u7ec6\u80de\uff1b<\/section>\n<\/li>\n<li>\n<section>\u8054\u5408\u6cbb\u7597\u7b56\u7565\u5982DC\u75ab\u82d7\u4e0e\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8054\u7528\uff0c\u663e\u8457\u63d0\u5347\u7597\u6548\u3002<\/section>\n<\/li>\n<\/ul>\n<h5>\uff08\u4e8c\uff09\u4ee3\u8c22\u6027\u75be\u75c5\uff1a\u91cd\u5851\u514d\u75ab\u4ee3\u8c22\u5e73\u8861<\/h5>\n<p>\u57281\u578b\u7cd6\u5c3f\u75c5\uff08T1DM\uff09\u4e2d\uff0cDCs\u5448\u9012\u80f0\u5c9b\u03b2\u7ec6\u80de\u81ea\u8eab\u6297\u539f\uff0c\u5bfc\u81f4\u03b2\u7ec6\u80de\u635f\u4f24\u3002\u901a\u8fc7\u7ef4\u751f\u7d20D\u2083\u3001\u96f7\u5e15\u9709\u7d20\u7b49\u4fee\u9970DCs\uff0c\u53ef\u8bf1\u5bfc\u514d\u75ab\u8010\u53d7\uff0c\u4fdd\u62a4\u80f0\u5c9b\u529f\u80fd\u3002\u4e34\u5e8a\u7814\u7a76\u663e\u793a\uff0c\u80f0\u5c9b\u7d20\u80bd\u8109\u51b2\u7684tolDCs\u80fd\u7a33\u5b9aT1DM\u60a3\u8005\u7684\u8840\u7cd6\u63a7\u5236\u3002<\/p>\n<h5>\uff08\u4e09\uff09\u611f\u67d3\u6027\u75be\u75c5\uff1a\u5bf9\u6297\u75c5\u539f\u4f53\u7684\u201c\u514d\u75ab\u589e\u5f3a\u5242\u201d<\/h5>\n<p>DCs\u901a\u8fc7TLR\u53d7\u4f53\u8bc6\u522b\u75c5\u6bd2\u3001\u7ec6\u83cc\u7b49\u75c5\u539f\u4f53\u7684PAMPs\uff0c\u542f\u52a8\u9488\u5bf9\u6027\u514d\u75ab\u5e94\u7b54\u3002\u81ea\u4f53DC\u75ab\u82d7\u5728\u6162\u6027HIV\u611f\u67d3\u4e2d\u53ef\u964d\u4f4e\u75c5\u6bd2\u8f7d\u91cf\uff0c\u6269\u589eHIV\u7279\u5f02\u6027T\u7ec6\u80de\uff1b\u9488\u5bf9COVID-19\u7684DC\u75ab\u82d7\uff0c\u80fd\u8bf1\u5bfc\u5f3a\u6548T\u7ec6\u80de\u514d\u75ab\uff0c\u4fdd\u62a4\u7387\u8fbe95.56%\u3002<\/p>\n<h5>\uff08\u56db\uff09\u81ea\u8eab\u514d\u75ab\u75c5\u4e0e\u79fb\u690d\uff1a\u8bf1\u5bfc\u514d\u75ab\u8010\u53d7<\/h5>\n<p>DCs\u53ef\u901a\u8fc7\u8bf1\u5bfc\u8c03\u8282\u6027T\u7ec6\u80de\u3001\u5206\u6ccc\u6291\u5236\u6027\u7ec6\u80de\u56e0\u5b50\uff0c\u6291\u5236\u75c5\u7406\u6027\u514d\u75ab\u53cd\u5e94\u3002\u5728\u5668\u5b98\u79fb\u690d\u4e2d\uff0cDCs\u65e2\u80fd\u4fc3\u8fdb\u79fb\u690d\u6392\u65a5\uff0c\u4e5f\u80fd\u8bf1\u5bfc\u514d\u75ab\u8010\u53d7\u2014\u2014\u901a\u8fc7\u57fa\u56e0\u5de5\u7a0b\u6539\u9020\u6216\u836f\u7269\u4fee\u9970DCs\uff0c\u53ef\u5ef6\u957f\u79fb\u690d\u7269\u5b58\u6d3b\u65f6\u95f4\u3002<\/p>\n<h2 data-pm-slice=\"2 2 []\">\u56db\u3001\u6842\u828e\u751f\u7269\uff1a\u8d4b\u80fdDC\u7597\u6cd5\u521b\u65b0\u5f00\u53d1<\/h2>\n<p>\u8981\u590d\u73b0\u6216\u8d85\u8d8a\u4e0a\u8ff0\u4e34\u5e8a\u6210\u679c\uff0c\u60a8\u9700\u8981\uff1a<strong>\u9ad8\u7eaf\u5ea6\u6297\u539f\u80bd + pMHC\u56db\u805a\u4f53 + \u5de5\u7a0b\u5316APC\u6784\u5efa<\/strong>\u3002\u6842\u828e\u751f\u7269\u5df2\u6784\u5efa\u5b8c\u6574\u5e73\u53f0\uff1a<\/p>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">1.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=136\" target=\"_blank\" rel=\"noopener\">\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u6269\u589e\uff1a <\/a><\/span><\/strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;span&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;font-size: 13px;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">\u6842\u828e\u62e5\u6709\u7a33\u5b9a\u7684\u6297\u539f\u7279\u5f02\u6027DC\u7684\u5206\u5316\u6210\u719f\u5de5\u827a\uff0c\u662f\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u6269\u589e\u548c\u68c0\u6d4b\u7684\u57fa\u77f3\u3002<\/span><\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">2.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=1192\" target=\"_blank\" rel=\"noopener\">\u5fae\u91cfpMHC\u590d\u5408\u7269\u5408\u6210\u670d\u52a1\uff1a\u00a0<\/a><\/span><\/strong>\u652f\u6301<span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;span&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;font-size: 13px;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">\u5305\u62ecHLA-A*02:01\u7b4930\u591a\u79cdHLA\u4e9a\u578b\u7684pMHC\uff0c\u7528\u4e8eDC\u529f\u80fd\u9a8c\u8bc1<\/span><\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">3.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=133\" target=\"_blank\" rel=\"noopener\">pMHC\u8367\u5149\u56db\u805a\u4f53\u5408\u6210\u4ee5\u53ca\u7b5b\u9009\uff1a <\/a><\/span><\/strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;span&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;font-size: 13px;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">\u73b0\u8d27\u8986\u76d6\u591a\u79cd\u80bf\u7624\u6297\u539f\uff08\u5982CMV\/EBV\/KRAS\u7b49\uff09\uff0c\u5feb\u901f\u5206\u9009\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de<\/span><\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">4.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=1489\" target=\"_blank\" rel=\"noopener\">\u5355\u514b\u9686TCR\u6d4b\u5e8f\uff1a\u00a0<\/a><\/span><\/strong>\u4ece\u56db\u805a\u4f53\u5206\u9009\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u4e2d\u914d\u5bf9TCR\u4e3b\u514b\u9686<\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">5. <\/span><\/strong><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\"><a href=\"https:\/\/www.guixiong.com.cn\/?page_id=1197\" target=\"_blank\" rel=\"noopener\">\u6297\u539f\u80bd-MHC\u4eb2\u548c\u529b\u9ad8\u901a\u91cfELISA\u626b\u63cf\u670d\u52a1\uff1a\u00a0<\/a><\/span><\/strong>\u9ad8\u901a\u91cf\u7b5b\u9009\u6700\u4f18\u65b0\u6297\u539f\u8868\u4f4d\uff0c\u6307\u5bfcDC\u75ab\u82d7\u8bbe\u8ba1<\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">7.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=546\" target=\"_blank\" rel=\"noopener\">\u5de5\u7a0b\u5316\u5448\u9012\u7ec6\u80de\u6784\u5efa\uff1a\u00a0<\/a><\/span><\/strong>K562-HLA\u7cfb\u5217<span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;span&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;font-size: 13px;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">\uff0c\u6a21\u62df\u4f53\u5185\u6297\u539f\u5448\u9012\uff0c\u7528\u4e8eDC\u529f\u80fd\u9a8c\u8bc1<\/span><\/p>\n<h2 data-pm-slice=\"2 2 []\">\u4e94\u3001\u5e94\u7528\u573a\u666f\u5efa\u8bae<\/h2>\n<ul 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