{"id":1646,"date":"2026-02-03T11:51:12","date_gmt":"2026-02-03T11:51:12","guid":{"rendered":"https:\/\/www.guixiong.com.cn\/?page_id=1646"},"modified":"2026-02-03T14:37:04","modified_gmt":"2026-02-03T14:37:04","slug":"%e4%b8%80%e7%af%87%e7%bb%8f%e5%85%b8%e7%bb%bc%e8%bf%b0%e8%b0%88%ef%bc%9atcr-t%e7%96%97%e6%b3%95%e7%9a%84%e7%90%86%e6%80%a7%e8%ae%be%e8%ae%a1%e4%b9%8b%e8%b7%af","status":"publish","type":"page","link":"https:\/\/www.guixiong.com.cn\/?page_id=1646","title":{"rendered":"\u4e00\u7bc7\u7ecf\u5178\u7efc\u8ff0\u8c08\uff1aTCR-T\u7597\u6cd5\u7684\u7406\u6027\u8bbe\u8ba1\u4e4b\u8def"},"content":{"rendered":"<blockquote>\n<pre data-pm-slice=\"2 2 []\">TCR\u4e0epMHC\u7684\u76f8\u4e92\u4f5c\u7528\u53d1\u751f\u5728\u539f\u5b50\u5c3a\u5ea6\u3002\u7406\u89e3\u5176\u52a8\u6001\u884c\u4e3a\uff0c\u662f\u8bbe\u8ba1\u9ad8\u4eb2\u548c\u529b\u3001\u9ad8\u7279\u5f02\u6027TCR-T\u7597\u6cd5\u7684\u5173\u952e\u3002\r\n\r\n<strong>\u5728TCR-T\u7ec6\u80de\u7597\u6cd5\u8fdb\u5165\u4e34\u5e8a\u7206\u53d1\u671f\u7684\u4eca\u5929\uff0c\u4e00\u4e2a\u6838\u5fc3\u6311\u6218\u4f9d\u7136\u5b58\u5728\uff1a\u5982\u4f55\u4ece\u6d77\u91cf\u5019\u9009TCR\u4e2d\uff0c\u5feb\u901f\u3001\u7cbe\u51c6\u5730\u7b5b\u9009\u51fa\u90a3\u4e9b\u65e2\u80fd\u5f3a\u529b\u7ed3\u5408\u80bf\u7624\u65b0\u6297\u539f\u3001\u53c8\u4e0d\u4f1a\u8bef\u4f24\u6b63\u5e38\u7ec4\u7ec7\u7684\u201c\u9ec4\u91d1TCR\u201d\uff1f<\/strong>\u7b54\u6848\uff0c\u6216\u8bb8\u5c31\u85cf\u5728\u5341\u5e74\u524d\u7684\u4e00\u7bc7\u88ab\u4f4e\u4f30\u7684\u7efc\u8ff0\u91cc\u30022015\u5e74\uff0c\u725b\u6d25\u5927\u5b66Charlotte Deane\u56e2\u961f\u5728<strong>\u300aBriefings in Bioinformatics\u300b<\/strong>\u4e0a\u53d1\u6587<a href=\"https:\/\/academic.oup.com\/bib\/article-lookup\/doi\/10.1093\/bib\/bbv005\" target=\"_blank\" rel=\"noopener\">Current status and future challenges in T-cell receptor\/peptide\/MHC molecular dynamics simulations<\/a>\uff0c\u7cfb\u7edf\u68b3\u7406\u4e86\u5229\u7528<strong>\u5206\u5b50\u52a8\u529b\u5b66\uff08MD\uff09\u6a21\u62df<\/strong>\u7814\u7a76TCR\/\u80bd\/MHC\uff08pMHC\uff09\u590d\u5408\u7269\u7684\u73b0\u72b6\u4e0e\u672a\u6765\u3002\u8fd9\u7bc7\u8bba\u6587\uff08PMID: 25725219\uff09\u4e0d\u4ec5\u662f\u4e00\u4efd\u6280\u672f\u62a5\u544a\uff0c\u66f4\u662f\u4e00\u5f20\u7cbe\u51c6\u7684\u8def\u7ebf\u56fe\uff0c\u9884\u8a00\u4e86\u4eca\u65e5TCR\u7406\u6027\u8bbe\u8ba1\u6240\u4f9d\u8d56\u7684\u8ba1\u7b97\u9769\u547d\u3002<\/pre>\n<\/blockquote>\n<h3>\u7b2c\u4e00\u7ae0\uff1a\u4e3a\u4f55\u9759\u6001\u7ed3\u6784\u4e0d\u8db3\u4ee5\u63ed\u793a\u514d\u75ab\u8bc6\u522b\u7684\u771f\u76f8\uff1f<\/h3>\n<p>T\u7ec6\u80de\u901a\u8fc7\u5176\u8868\u9762\u7684T\u7ec6\u80de\u53d7\u4f53\uff08TCR\uff09\u6765\u626b\u63cf\u7531MHC-I\u5206\u5b50\u5448\u9012\u7684\u6297\u539f\u80bd\uff08\u5373pMHC\uff09\u3002\u4f20\u7edfX\u5c04\u7ebf\u6676\u4f53\u5b66\u4e3a\u6211\u4eec\u63d0\u4f9b\u4e86\u9ad8\u5206\u8fa8\u7387\u7684\u590d\u5408\u7269\u201c\u5feb\u7167\u201d\uff0c\u4f46\u8fd9\u4e9b\u7ed3\u6784\u5f80\u5f80\u662f\u80fd\u91cf\u6700\u4f4e\u3001\u6700\u7a33\u5b9a\u7684\u6784\u8c61\u3002<\/p>\n<p>\u7136\u800c\uff0c\u771f\u5b9e\u7684\u514d\u75ab\u8bc6\u522b\u662f\u4e00\u4e2a**\u9ad8\u5ea6\u52a8\u6001\u7684\u8fc7\u7a0b**\u3002TCR\u4e0epMHC\u7684\u7ed3\u5408\u6d89\u53ca\uff1a<\/p>\n<ul class=\"list-paddingleft-1\">\n<li><strong>\u67d4\u6027\u8bf1\u5bfc<\/strong><br \/>\n<section>\u80bd\u6bb5\u548cTCR\u7684\u4e92\u8865\u51b3\u5b9a\u533a\uff08CDR\uff09\u73af\u4f1a\u53d1\u751f\u6784\u8c61\u8c03\u6574\uff1b<\/section>\n<\/li>\n<li><strong>\u6c34\u5206\u5b50\u4ecb\u5bfc<\/strong><br \/>\n<section>\u754c\u9762\u6c34\u5206\u5b50\u7f51\u7edc\u7684\u5f62\u6210\u4e0e\u89e3\u79bb\u5bf9\u7ed3\u5408\u80fd\u81f3\u5173\u91cd\u8981\uff1b<\/section>\n<\/li>\n<li><strong>\u77ac\u65f6\u76f8\u4e92\u4f5c\u7528<\/strong><br \/>\n<section>\u6c22\u952e\u3001\u76d0\u6865\u3001\u8303\u5fb7\u534e\u529b\u7b49\u5728\u7eb3\u79d2\u5c3a\u5ea6\u4e0a\u4e0d\u65ad\u5f62\u6210\u4e0e\u65ad\u88c2\u3002<\/section>\n<\/li>\n<\/ul>\n<p>\u8fd9\u4e9b**\u6beb\u79d2\u751a\u81f3\u7eb3\u79d2\u7ea7\u522b\u7684\u7ec6\u5fae\u52a8\u6001**\uff0c\u6070\u6070\u51b3\u5b9a\u4e86TCR\u7ed3\u5408\u7684\u4eb2\u548c\u529b\u3001\u4ea4\u53c9\u53cd\u5e94\u6027\u548c\u6700\u7ec8\u7684T\u7ec6\u80de\u6fc0\u6d3b\u6548\u7387\u3002\u800c\u8fd9\u4e9b\u4fe1\u606f\uff0c\u662f\u9759\u6001\u7ed3\u6784\u65e0\u6cd5\u63d0\u4f9b\u7684\u3002<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Current-status-and-future-challenges-in-T-cell-receptor-1.jpg\" \/><\/p>\n<h3>\u7b2c\u4e8c\u7ae0\uff1a2015\u5e74\u7684\u5168\u666f\u56fe\u2014\u2014\u65b9\u6cd5\u3001\u6d1e\u89c1\u4e0e\u6838\u5fc3\u6311\u6218<\/h3>\n<p>Knapp\u7b49\u4eba\u5728\u7efc\u8ff0\u4e2d\u7cfb\u7edf\u6027\u5730\u603b\u7ed3\u4e86\u5f53\u65f6\u7684\u7814\u7a76\u8303\u5f0f\uff0c\u5e76\u6307\u51fa\u4e86\u4e09\u5927\u5173\u952e\u6311\u6218\uff1a<\/p>\n<section><strong>\u5efa\u6a21\u4e0e\u529b\u573a\u7684\u51c6\u786e\u6027<\/strong><\/section>\n<section>\u521d\u59cb\u7ed3\u6784\u591a\u4f9d\u8d56\u540c\u6e90\u5efa\u6a21\uff0c\u800c\u901a\u7528\u529b\u573a\uff08\u5982AMBER, CHARMM\uff09\u5728\u63cf\u8ff0\u86cb\u767d\u8d28-\u80bd-MHC\u8fd9\u7c7b\u590d\u6742\u4f53\u7cfb\u65f6\u53ef\u80fd\u5b58\u5728\u504f\u5dee\u3002<\/section>\n<section><strong>\u91c7\u6837\u4e0d\u8db3\uff08Sampling Problem\uff09<\/strong><\/section>\n<section>\u53d7\u9650\u4e8e\u5f53\u65f6\u7684\u7b97\u529b\uff0c\u6a21\u62df\u65f6\u95f4\u901a\u5e38\u53ea\u6709\u51e0\u5341\u5230\u51e0\u767e\u7eb3\u79d2\uff0c\u8fdc\u4e0d\u8db3\u4ee5\u6355\u6349\u5230\u6162\u901f\u7684\u6784\u8c61\u53d8\u5316\uff08\u5982CDR3\u73af\u7684\u5927\u89c4\u6a21\u91cd\u6392\uff09\uff0c\u5bfc\u81f4\u7ed3\u679c\u53ef\u80fd\u53ea\u662f\u5c40\u90e8\u80fd\u91cf\u6700\u5c0f\u503c\u3002<\/section>\n<section><strong>\u5206\u6790\u65b9\u6cd5\u7684\u6807\u51c6\u5316\u7f3a\u5931<\/strong><\/section>\n<section>\u4e0d\u540c\u7814\u7a76\u7ec4\u4f7f\u7528\u4e0d\u540c\u7684\u6307\u6807\uff08RMSD, RMSF, \u6c22\u952e\u3001\u7ed3\u5408\u81ea\u7531\u80fd\u7b49\uff09\u6765\u8bc4\u4f30\u7a33\u5b9a\u6027\uff0c\u4f7f\u5f97\u7ed3\u679c\u96be\u4ee5\u6a2a\u5411\u6bd4\u8f83\u3002<\/section>\n<p>\u66f4\u91cd\u8981\u7684\u662f\uff0c\u4f5c\u8005\u654f\u9510\u5730\u6307\u51fa\uff1a**TCR-pMHC\u7684\u76f8\u4e92\u4f5c\u7528\u6a21\u5f0f\u5177\u6709\u9ad8\u5ea6\u591a\u6837\u6027**\u3002\u4e0d\u5b58\u5728\u4e00\u4e2a\u653e\u4e4b\u56db\u6d77\u800c\u7686\u51c6\u7684\u201c\u901a\u7528\u6a21\u578b\u201d\uff0c\u5fc5\u987b\u9488\u5bf9\u6bcf\u4e2a\u7279\u5b9a\u7684\u590d\u5408\u7269\u8fdb\u884c\u7ec6\u81f4\u5206\u6790\u3002<\/p>\n<section><img decoding=\"async\" src=\"https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Current-status-and-future-challenges-in-T-cell-receptor-2.jpg\" \/><\/section>\n<h3>\u7b2c\u4e09\u7ae0\uff1a\u5341\u5e74\u8de8\u8d8a\u2014\u2014\u4ece\u6311\u6218\u5230\u89e3\u51b3\u65b9\u6848<\/h3>\n<p>\u56de\u671b\u8fc7\u53bb\u5341\u5e74\uff0c\u7efc\u8ff0\u4e2d\u63d0\u51fa\u7684\u6311\u6218\u6b63\u88ab\u4e00\u4e00\u653b\u514b\uff1a<\/p>\n<ul class=\"list-paddingleft-1\">\n<li><strong>AI\u9a71\u52a8\u7684\u7ed3\u6784\u9884\u6d4b<\/strong><br \/>\n<section>AlphaFold2\u548cRoseTTAFold\u7684\u51fa\u73b0\uff0c\u6781\u5927\u63d0\u5347\u4e86TCR-pMHC\u590d\u5408\u7269\u521d\u59cb\u6a21\u578b\u7684\u51c6\u786e\u6027\uff0c\u4e3a\u540e\u7eedMD\u6a21\u62df\u5960\u5b9a\u4e86\u575a\u5b9e\u57fa\u7840\u3002<\/section>\n<\/li>\n<li><strong>\u7b97\u529b\u9769\u547d<\/strong><br \/>\n<section>GPU\u96c6\u7fa4\u548c\u4e13\u7528\u786c\u4ef6\uff08\u5982Anton\uff09\u5c06\u6a21\u62df\u65f6\u957f\u63a8\u8fdb\u81f3\u5fae\u79d2\u4e43\u81f3\u6beb\u79d2\u7ea7\u522b\uff0c\u8db3\u4ee5\u89c2\u5bdf\u5230\u529f\u80fd\u76f8\u5173\u7684\u6162\u901f\u52a8\u529b\u5b66\u8fc7\u7a0b\u3002<\/section>\n<\/li>\n<li><strong>\u589e\u5f3a\u91c7\u6837\u7b97\u6cd5<\/strong><br \/>\n<section>\u5143\u52a8\u529b\u5b66\uff08Metadynamics\uff09\u3001\u526f\u672c\u4ea4\u6362\uff08REMD\uff09\u7b49\u65b9\u6cd5\u80fd\u6709\u6548\u8de8\u8d8a\u80fd\u91cf\u58c1\u5792\uff0c\u63a2\u7d22\u66f4\u5e7f\u9614\u7684\u6784\u8c61\u7a7a\u95f4\u3002<\/section>\n<\/li>\n<li><strong>\u591a\u5c3a\u5ea6\u5efa\u6a21<\/strong><br \/>\n<section>\u4ece\u5168\u539f\u5b50MD\u5230\u7c97\u7c92\u5316\u6a21\u578b\uff0c\u518d\u5230\u673a\u5668\u5b66\u4e60\u52bf\u51fd\u6570\uff0c\u5f62\u6210\u4e86\u8986\u76d6\u4e0d\u540c\u65f6\u95f4\u548c\u7a7a\u95f4\u5c3a\u5ea6\u7684\u5b8c\u6574\u5de5\u5177\u94fe\u3002<\/section>\n<\/li>\n<\/ul>\n<p>\u5982\u4eca\uff0cMD\u6a21\u62df\u5df2\u4e0d\u518d\u662f\u7eaf\u7cb9\u7684\u5b66\u672f\u63a2\u7d22\uff0c\u800c\u662f**TCR\u4eb2\u548c\u529b\u6210\u719f\u3001\u7279\u5f02\u6027\u8bc4\u4f30\u548c\u8131\u9776\u98ce\u9669\u9884\u6d4b**\u7684\u6838\u5fc3\u73af\u8282\u3002<\/p>\n<h2>\u7ed3\u8bed\uff1a\u7ad9\u5728\u5de8\u4eba\u7684\u80a9\u8180\u4e0a\uff0c\u8d70\u5411\u7cbe\u51c6\u514d\u75ab\u6cbb\u7597\u7684\u672a\u6765<\/h2>\n<p>Knapp\u7b49\u4eba\u7684\u8fd9\u7bc7\u7efc\u8ff0\uff0c\u5982\u540c\u4e00\u5ea7\u706f\u5854\uff0c\u5728TCR\u8ba1\u7b97\u751f\u7269\u5b66\u7684\u65e9\u671f\u8ff7\u96fe\u4e2d\u6307\u660e\u4e86\u65b9\u5411\u3002\u5b83\u544a\u8bc9\u6211\u4eec\uff0c\u8981\u771f\u6b63\u9a7e\u9a6dT\u7ec6\u80de\u7684\u8bc6\u522b\u80fd\u529b\uff0c\u5c31\u5fc5\u987b\u6df1\u5165\u5230\u539f\u5b50\u8fd0\u52a8\u7684\u5c42\u9762\u3002<\/p>\n<p>\u4eca\u5929\uff0c\u968f\u7740\u5b9e\u9a8c\u6280\u672f\u4e0e\u8ba1\u7b97\u79d1\u5b66\u7684\u6df1\u5ea6\u878d\u5408\uff0c\u6211\u4eec\u5df2\u7ecf\u80fd\u591f\u6784\u5efa\u4e00\u4e2a\u201c**\u53d1\u73b0-\u9a8c\u8bc1-\u4f18\u5316**\u201d\u7684\u5b8c\u6574\u95ed\u73af\u3002\u6842\u828e\u751f\u7269\u6b63\u662f\u8fd9\u4e00\u8d8b\u52bf\u7684\u8df5\u884c\u8005\uff0c\u81f4\u529b\u4e8e\u5c06\u6700\u524d\u6cbf\u7684\u79d1\u5b66\u6d1e\u89c1\uff0c\u8f6c\u5316\u4e3a\u653b\u514b\u764c\u75c7\u7684\u6709\u529b\u6b66\u5668\u3002<\/p>\n<p>\u4ece\u5341\u5e74\u524d\u7684\u4e00\u7bc7\u7efc\u8ff0\uff0c\u5230\u4eca\u5929\u62ef\u6551\u751f\u547d\u7684\u7597\u6cd5\uff0c\u8fd9\u6b63\u662f\u57fa\u7840\u79d1\u5b66\u7814\u7a76\u6700\u52a8\u4eba\u7684\u529b\u91cf\u3002<\/p>\n<h3>\u6842\u828e\u751f\u7269\uff1a\u63d0\u4f9b\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u5168\u94fe\u6761\u89e3\u51b3\u65b9\u6848<\/h3>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">1.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=136\" target=\"_blank\" rel=\"noopener\">\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u6269\u589e\uff1a\u00a0<\/a><\/span><\/strong>\u8986\u76d6\u9ed1\u8272\u7d20\u7624\u6838\u5fc3\u6297\u539f\uff08MART-1\/gp100\/NY-ESO-1\u7b49\uff09\uff0c\u652f\u6301HLA-A*02:01\u7b49\u4e3b\u6d41\u7b49\u4f4d\u57fa\u56e0<\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">2.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=1192\" target=\"_blank\" rel=\"noopener\">\u5fae\u91cfpMHC\u590d\u5408\u7269\u5408\u6210\u670d\u52a1\uff1a\u00a0<\/a><\/span><\/strong>\u5feb\u901f\u5b9a\u5236\uff0c\u5c11\u91cf\u9a8c\u8bc1\uff0c\u540c\u6b65\u8ffd\u8e2a\u591a\u4e2a\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u514b\u9686<\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">3.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=133\" target=\"_blank\" rel=\"noopener\">pMHC\u8367\u5149\u56db\u805a\u4f53\u5408\u6210\u4ee5\u53ca\u7b5b\u9009\uff1a\u00a0<\/a><\/span><\/strong>\u57fa\u4e8e\u56db\u805a\u4f53\u5206\u9009\u7ec6\u80de\uff0c\u6269\u589e\u9ad8\u7eaf\u5ea6T-bet\u207a\u529f\u80fd\u6027T\u7ec6\u80de<\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">4.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=1489\" target=\"_blank\" rel=\"noopener\">\u5355\u514b\u9686TCR\u6d4b\u5e8f\uff1a\u00a0<\/a><\/span><\/strong>\u4ece\u56db\u805a\u4f53\u5206\u9009\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u4e2d\u914d\u5bf9TCR\u4e3b\u514b\u9686<\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">5.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=558\" target=\"_blank\" rel=\"noopener\">\u7a33\u8f6c\u539f\u4ee3TCR-T\u6784\u5efa\uff1a\u00a0<\/a><\/span><\/strong>\u6574\u5408murine TCR\u6052\u5b9a\u533a\u7684\u975e\u75c5\u6bd2TCR\u7a33\u8f6c\u7cfb\u7edf\uff0c\u66f4\u5b89\u5168\u7684\u4e34\u5e8a\u524d\u7814\u7a76\u5e94\u7528<\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">6.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=1197\" target=\"_blank\" rel=\"noopener\">\u6297\u539f\u80bd-MHC\u4eb2\u548c\u529b\u9ad8\u901a\u91cfELISA\u626b\u63cf\u670d\u52a1\uff1a\u00a0<\/a><\/span><\/strong>\u9ad8\u901a\u91cf\u7b5b\u9009\u6700\u4f18\u65b0\u6297\u539f\u8868\u4f4d\uff0c\u6307\u5bfc\u80bd\u6bb5\u7b5b\u9009<\/p>\n<section><\/section>\n<section><\/section>\n<p><strong><span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">7.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=546\" target=\"_blank\" rel=\"noopener\">\u5de5\u7a0b\u5316\u5448\u9012\u7ec6\u80de\u6784\u5efa\uff1a\u00a0<\/a><\/span><\/strong>K562-HLA\u7cfb\u5217\uff0c\u6a21\u62df\u4f53\u5185\u6297\u539f\u5448\u9012\uff0c\u7528\u4e8eTCR\u529f\u80fd\u9a8c\u8bc1<\/p>\n<p>Views: 6<\/p>","protected":false},"excerpt":{"rendered":"<p>TCR\u4e0epMHC\u7684\u76f8\u4e92\u4f5c\u7528\u53d1\u751f\u5728\u539f\u5b50\u5c3a\u5ea6\u3002\u7406\u89e3\u5176\u52a8\u6001\u884c\u4e3a\uff0c\u662f\u8bbe\u8ba1\u9ad8\u4eb2\u548c\u529b\u3001\u9ad8\u7279\u5f02\u6027TCR-T\u7597\u6cd5\u7684\u5173\u952e\u3002 \u5728T&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"default","_kad_post_title":"default","_kad_post_layout":"default","_kad_post_sidebar_id":"","_kad_post_content_style":"default","_kad_post_vertical_padding":"default","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"class_list":["post-1646","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/1646","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1646"}],"version-history":[{"count":2,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/1646\/revisions"}],"predecessor-version":[{"id":1650,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/1646\/revisions\/1650"}],"wp:attachment":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1646"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}