{"id":1674,"date":"2026-02-12T15:02:53","date_gmt":"2026-02-12T15:02:53","guid":{"rendered":"https:\/\/www.guixiong.com.cn\/?page_id=1674"},"modified":"2026-02-12T15:07:03","modified_gmt":"2026-02-12T15:07:03","slug":"%e7%96%8f%e6%b0%b4%e4%bd%9c%e7%94%a8%e5%8a%9b%e4%b8%bb%e5%af%bct%e7%bb%86%e8%83%9e%e8%af%86%e5%88%abkras-g12v%e7%aa%81%e5%8f%98","status":"publish","type":"page","link":"https:\/\/www.guixiong.com.cn\/?page_id=1674","title":{"rendered":"\u758f\u6c34\u4f5c\u7528\u529b\u4e3b\u5bfcT\u7ec6\u80de\u8bc6\u522bKRAS G12V\u7a81\u53d8"},"content":{"rendered":"<blockquote>\n<pre data-pm-slice=\"2 2 []\">\u7814\u7a76\u63ed\u793a\uff0c\u4e00\u4e2a\u540d\u4e3aV2\u7684T\u7ec6\u80de\u6a21\u62df\u6297\u4f53\uff08TCRm\uff09\uff0c\u901a\u8fc7\u5f62\u6210\u4e00\u4e2a\u7531\u758f\u6c34\u6c28\u57fa\u9178\u6784\u6210\u7684\u201c\u7b3c\u5b50\u201d\uff0c\u7cbe\u51c6\u6355\u83b7\u5e76\u8bc6\u522bKRAS G12V\u7a81\u53d8\u4ea7\u751f\u7684\u65b0\u6297\u539f\u80bd\u3002\r\n\r\n<strong>KRAS G12V\u662f\u80f0\u817a\u764c\u3001\u80ba\u764c\u7b49\u201c\u764c\u738b\u201d\u7684\u5e38\u89c1\u9a71\u52a8\u7a81\u53d8\uff0c\u4f46\u56e0\u5176\u4f4d\u4e8e\u7ec6\u80de\u5185\uff0c\u4f20\u7edf\u6297\u4f53\u836f\u7269\u96be\u4ee5\u89e6\u53ca\u3002<\/strong>\u00a0\u514d\u75ab\u7597\u6cd5\u63d0\u4f9b\u4e86\u4e00\u6761\u65b0\u8def\uff1a\u5229\u7528T\u7ec6\u80de\u6765\u8bc6\u522b\u7531HLA\u5206\u5b50\u5448\u9012\u5230\u7ec6\u80de\u8868\u9762\u7684KRAS G12V\u7a81\u53d8\u80bd\u6bb5\uff08\u65b0\u6297\u539f\uff09\u3002\u7136\u800c\uff0c\u5982\u4f55\u8ba9T\u7ec6\u80de\u6216\u5176\u5de5\u7a0b\u5316\u4ea7\u7269\uff08\u5982TCR-T\u3001\u53cc\u7279\u5f02\u6027\u6297\u4f53\uff09\u7cbe\u51c6\u533a\u5206\u201c\u7a81\u53d8\u201d\u4e0e\u201c\u91ce\u751f\u578b\u201d\uff08\u4ec5\u4e00\u4e2a\u6c28\u57fa\u9178\u4e4b\u5dee\uff09\uff0c\u662f\u5de8\u5927\u7684\u6311\u6218\u3002\u8fd1\u65e5\uff0c\u7ea6\u7ff0\u970d\u666e\u91d1\u65af\u5927\u5b66\u56e2\u961f\u5728<strong>\u300aNature Communications\u300b<\/strong>\u4e0a\u53d1\u8868\u91cd\u78c5\u7814\u7a76\uff0c\u9996\u6b21\u5229\u7528\u51b7\u51bb\u7535\u955c\uff08cryo-EM\uff09\u6280\u672f\uff0c\u4ece\u539f\u5b50\u5c42\u9762\u63ed\u793a\u4e86\u8fd9\u4e00\u7cbe\u51c6\u8bc6\u522b\u7684\u5965\u79d8\u2014\u2014<strong>\u758f\u6c34\u4f5c\u7528\u529b<\/strong>\uff08Hydrophobic Interactions\uff09\u3002<\/pre>\n<\/blockquote>\n<h3>\u7a81\u7834\uff1a\u770b\u6e05\u201c\u5bfc\u5f39\u201d\u4e0e\u201c\u9776\u6807\u201d\u7684\u539f\u5b50\u7ea7\u5bf9\u63a5<\/h3>\n<p>\u7814\u7a76\u56e2\u961f\u805a\u7126\u4e8e\u4e00\u79cd\u540d\u4e3a<strong>V2<\/strong>\u7684T\u7ec6\u80de\u53d7\u4f53\u6a21\u62df\u6297\u4f53\uff08TCR mimic, TCRm\uff09\u3002\u8fd9\u662f\u4e00\u79cd\u80fd\u50cfT\u7ec6\u80de\u4e00\u6837\u8bc6\u522bHLA-\u65b0\u6297\u539f\u590d\u5408\u7269\u7684\u5de5\u7a0b\u5316\u6297\u4f53\u3002\u4ed6\u4eec\u6210\u529f\u89e3\u6790\u4e86V2\u6297\u4f53\u4e0eKRAS G12V\u80bd\u6bb5-HLA-A*03:01\u590d\u5408\u7269\u7684\u9ad8\u5206\u8fa8\u7387\uff083.14 \u00c5\uff09\u51b7\u51bb\u7535\u955c\u7ed3\u6784\u3002<\/p>\n<p>\u7ed3\u6784\u663e\u793a\uff0cV2\u6297\u4f53\u5e76\u975e\u5168\u9762\u8986\u76d6\u6574\u4e2a\u80bd\u6bb5\uff0c\u800c\u662f**\u9ad8\u5ea6\u503e\u659c\u5730\u201c\u5750\u201d\u5728\u80bd\u6bb5\u7684C\u7aef**\uff0c\u5176\u4e92\u8865\u51b3\u5b9a\u533a\uff08CDR\uff09\u73af\uff0c\u7279\u522b\u662fCDR H3\uff0c\u76f4\u63a5\u5bf9\u51c6\u4e86\u5173\u952e\u7684G12V\u7a81\u53d8\u4f4d\u70b9\u3002<\/p>\n<h3>\u6838\u5fc3\u673a\u5236\uff1a\u4e00\u4e2a\u7cbe\u5de7\u7684\u201c\u758f\u6c34\u7b3c\u5b50\u201d<\/h3>\n<p>\u6700\u4ee4\u4eba\u60ca\u53f9\u7684\u53d1\u73b0\u662f\u8bc6\u522b\u7684\u5316\u5b66\u672c\u8d28\u3002V2\u6297\u4f53\u7684CDR H3\u548cCDR L2\u533a\u57df\u7684\u51e0\u4e2a\u5173\u952e\u6c28\u57fa\u9178\uff08Pro103H3, Val104H3, Tyr105H3, Phe53L2\uff09\u5171\u540c\u6784\u6210\u4e86\u4e00\u4e2a**\u677e\u6563\u7684\u758f\u6c34\u6027\u201c\u7b3c\u5b50\u201d**\u3002<\/p>\n<ul class=\"list-paddingleft-1\">\n<li><strong>\u5bf9\u4e8eG12V\u7a81\u53d8\u4f53<\/strong><br \/>\n<section>\u7a81\u53d8\u4ea7\u751f\u7684\u7f2c\u6c28\u9178\uff08Valine\uff09\u662f\u4e00\u4e2a**\u758f\u6c34\u6027**\u6c28\u57fa\u9178\u3002\u5b83\u6070\u597d\u80fd\u88ab\u8fd9\u4e2a\u201c\u758f\u6c34\u7b3c\u5b50\u201d\u5b8c\u7f8e\u5305\u88f9\uff0c\u901a\u8fc7\u5f3a\u5927\u7684\u758f\u6c34\u4f5c\u7528\u529b\u5b9e\u73b0\u7a33\u5b9a\u7ed3\u5408\u3002<\/section>\n<\/li>\n<li><strong>\u5bf9\u4e8e\u91ce\u751f\u578bG12<\/strong><br \/>\n<section>\u91ce\u751f\u578b\u662f\u7518\u6c28\u9178\uff08Glycine\uff09\uff0c\u5b83**\u6ca1\u6709\u4fa7\u94fe**\uff0c\u65e0\u6cd5\u4e0e\u8fd9\u4e2a\u758f\u6c34\u7b3c\u5b50\u5f62\u6210\u4efb\u4f55\u6709\u6548\u7684\u76f8\u4e92\u4f5c\u7528\uff0c\u56e0\u6b64\u65e0\u6cd5\u88ab\u6709\u6548\u8bc6\u522b\u3002<\/section>\n<\/li>\n<\/ul>\n<p>\u8fd9\u4e00\u673a\u5236\u89e3\u91ca\u4e86V2\u6297\u4f53\u4e3a\u4f55\u80fd\u5b9e\u73b0\u60ca\u4eba\u7684\u7279\u5f02\u6027\u2014\u2014**\u4e0d\u662f\u9760\u8bc6\u522b\u7a81\u53d8\u5e26\u6765\u7684\u65b0\u5316\u5b66\u57fa\u56e2\uff0c\u800c\u662f\u9760\u8bc6\u522b\u7a81\u53d8\u5e26\u6765\u7684\u201c\u758f\u6c34\u6027\u201d**\u3002<\/p>\n<section><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone size-full wp-image-1677\" src=\"https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-1.jpg\" alt=\"\" width=\"910\" height=\"926\" srcset=\"https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-1.jpg 910w, https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-1-295x300.jpg 295w, https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-1-768x782.jpg 768w\" sizes=\"(max-width: 910px) 100vw, 910px\" \/><\/section>\n<p>&nbsp;<\/p>\n<h3>\u610f\u5916\u6536\u83b7\uff1a\u6297\u4f53\u8fd8\u80fd\u201c\u8bf1\u5bfc\u5951\u5408\u201d<\/h3>\n<p>\u7814\u7a76\u8fd8\u6709\u53e6\u4e00\u9879\u91cd\u8981\u53d1\u73b0\u3002\u901a\u8fc7\u6bd4\u8f83V2\u6297\u4f53\u7ed3\u5408\u524d\u540e\u7684KRAS G12V\u80bd\u6bb5\u7ed3\u6784\uff0c\u4ed6\u4eec\u53d1\u73b0V2\u7684\u7ed3\u5408**\u8bf1\u5bfc\u4e86\u80bd\u6bb5\u53d1\u751f\u663e\u8457\u7684\u6784\u8c61\u53d8\u5316**\uff08Induced Fit\uff09\u3002<\/p>\n<p>\u5728\u672a\u7ed3\u5408\u72b6\u6001\u4e0b\uff0c\u80bd\u6bb5\u76f8\u5bf9\u5e73\u76f4\uff1b\u800c\u4e00\u65e6V2\u6297\u4f53\u7ed3\u5408\uff0c\u80bd\u6bb5\u7684C\u7aef\uff08\u7279\u522b\u662fLys16\uff09\u4f1a\u88ab\u63a8\u5f97\u66f4\u6df1\u5730\u5d4c\u5165HLA\u7684\u7ed3\u5408\u69fd\u4e2d\uff0c\u4ece\u800c\u5e26\u52a8\u6574\u4e2a\u80bd\u6bb5\u53d1\u751fN\u7aef\u4f4d\u79fb\u3002\u8fd9\u79cd\u52a8\u6001\u7684\u201c\u8bf1\u5bfc\u5951\u5408\u201d\u8fc7\u7a0b\uff0c\u8fdb\u4e00\u6b65\u589e\u5f3a\u4e86V2\u5bf9\u6297\u539f\u7684\u7279\u5f02\u6027\u8bc6\u522b\u80fd\u529b\u3002<\/p>\n<section><b id=\"Fig2\" class=\"c-article-section__figure-caption\" data-test=\"figure-caption-text\">Structure of V2-Fab\/KRAS<sup>G12V<\/sup>-HLA-A*03:01<\/b><\/section>\n<section><img decoding=\"async\" class=\"alignnone size-full wp-image-1676\" src=\"https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-2.jpg\" alt=\"\" width=\"937\" height=\"1002\" srcset=\"https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-2.jpg 937w, https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-2-281x300.jpg 281w, https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-2-768x821.jpg 768w\" sizes=\"(max-width: 937px) 100vw, 937px\" \/><\/section>\n<section><b id=\"Fig3\" class=\"c-article-section__figure-caption\" data-test=\"figure-caption-text\">\u00a0Structural basis of recognition of V2-Fab.<\/b><\/section>\n<section><img decoding=\"async\" class=\"alignnone size-full wp-image-1675\" src=\"https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-3.jpg\" alt=\"\" width=\"905\" height=\"932\" srcset=\"https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-3.jpg 905w, https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-3-291x300.jpg 291w, https:\/\/guixiong.com.cn\/wp-content\/uploads\/2026\/02\/Hydrophobic-interactions-dominate-the-recognition-of-a-KRAS-G12V-neoantigen-3-768x791.jpg 768w\" sizes=\"(max-width: 905px) 100vw, 905px\" \/><\/section>\n<section><\/section>\n<p>&nbsp;<\/p>\n<h3>\u542f\u793a\uff1a\u4e3a\u201c\u4e0d\u53ef\u6210\u836f\u201d\u9776\u70b9\u8bbe\u8ba1\u7cbe\u51c6\u6b66\u5668<\/h3>\n<p>\u8fd9\u9879\u7814\u7a76\u7684\u610f\u4e49\u8fdc\u4e0d\u6b62\u4e8eKRAS G12V\u672c\u8eab\u3002\u5b83\u63d0\u4f9b\u4e86\u4e00\u4e2a\u6e05\u6670\u7684\u8bbe\u8ba1\u84dd\u56fe\uff1a\u5bf9\u4e8e\u7531**\u758f\u6c34\u6027\u7a81\u53d8**\uff08\u5982G12V, G12C\uff09\u4ea7\u751f\u7684\u65b0\u6297\u539f\uff0c\u53ef\u4ee5\u4f18\u5148\u8003\u8651\u8bbe\u8ba1\u80fd\u591f\u5f62\u6210**\u758f\u6c34\u53e3\u888b\u6216\u7b3c\u5b50**\u7684TCR\u6216TCRm\u6297\u4f53\u3002\u540c\u65f6\uff0c\u7814\u7a76\u4e5f\u63d0\u9192\u6211\u4eec\uff0c\u5728\u6297\u4f53\u5de5\u7a0b\u5316\u6539\u9020\uff08\u4eb2\u548c\u529b\u6210\u719f\uff09\u8fc7\u7a0b\u4e2d\uff0c\u5fc5\u987b\u8c28\u614e\u884c\u4e8b\u3002\u6587\u4e2d\u5c1d\u8bd5\u7684\u591a\u4e2a\u7a81\u53d8\u867d\u7136\u63d0\u9ad8\u4e86\u4f53\u5916\u7ed3\u5408\u529b\uff0c\u5374\u672a\u80fd\u63d0\u5347\u751a\u81f3\u635f\u5bb3\u4e86T\u7ec6\u80de\u529f\u80fd\uff0c\u51f8\u663e\u4e86**\u529f\u80fd\u9a8c\u8bc1**\u7684\u4e0d\u53ef\u6216\u7f3a\u6027\u3002<\/p>\n<p>\u672a\u6765\uff0c\u7ed3\u5408\u7ed3\u6784\u751f\u7269\u5b66\u6307\u5bfc\u7684\u7406\u6027\u8bbe\u8ba1\u4e0e\u9ad8\u901a\u91cf\u7684\u529f\u80fd\u7b5b\u9009\uff0c\u5c06\u662f\u653b\u514bKRAS\u7b49\u201c\u4e0d\u53ef\u6210\u836f\u201d\u9776\u70b9\u7684\u5173\u952e\u3002<\/p>\n<p><strong>\u603b\u7ed3\u800c\u8a00<\/strong>\uff0c\u8fd9\u9879\u6765\u81ea\u9876\u5c16\u56e2\u961f\u7684\u7814\u7a76\uff0c\u5982\u540c\u4e00\u6b21\u7cbe\u5999\u7684\u201c\u5206\u5b50\u62c6\u5f39\u201d\uff0c\u5728\u539f\u5b50\u5c3a\u5ea6\u4e0a\u63ed\u793a\u4e86\u514d\u75ab\u7cfb\u7edf\u5982\u4f55\u7cbe\u51c6\u8bc6\u522b\u764c\u7ec6\u80de\u7684\u201c\u8eab\u4efd\u5bc6\u7801\u201d\u3002\u8fd9\u4e0d\u4ec5\u52a0\u6df1\u4e86\u6211\u4eec\u5bf9\u57fa\u7840\u514d\u75ab\u5b66\u7684\u7406\u89e3\uff0c\u66f4\u4e3a\u5f00\u53d1\u4e0b\u4e00\u4ee3\u66f4\u5b89\u5168\u3001\u66f4\u6709\u6548\u7684T\u7ec6\u80de\u7597\u6cd5\u94fa\u5e73\u4e86\u9053\u8def\u3002<\/p>\n<p data-test=\"article-title\" data-pm-slice=\"0 0 []\">\u53c2\u8003\u6587\u732e\uff1a<a href=\"https:\/\/www.nature.com\/articles\/s41467-023-40821-w\" target=\"_blank\" rel=\"noopener\">Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.<\/a>\u00a0 Nature Communications, 2023<\/p>\n<h3><span data-pm-slice=\"1 1 [&quot;heading&quot;,{&quot;tagName&quot;:&quot;h2&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;-webkit-tap-highlight-color: rgba(0, 0, 0, 0);margin: 30px 0px 15px;padding: 0px 0px 6px;outline: 0px;font-weight: 400;font-size: 19px;max-width: 100%;box-sizing: border-box !important;overflow-wrap: break-word !important;font-style: normal;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-indent: 0px;text-transform: none;widows: 2;word-spacing: 0px;-webkit-text-stroke-width: 0px;white-space: normal;background-color: rgb(255, 255, 255);text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;scrollbar-width: none;font-family: \\&quot;PingFang SC\\&quot;, \\&quot;Helvetica Neue\\&quot;, Helvetica, Arial, sans-serif;letter-spacing: normal;text-align: start;color: rgb(25, 118, 210);border-bottom: 1px solid rgb(238, 238, 238);&quot;,&quot;data-pm-slice&quot;:&quot;2 1 []&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;,&quot;level&quot;:2}]\">\u5982\u4f55\u5c06\u8f6c\u5316\u4e3a\u7814\u7a76\u6210\u679c\uff1f<\/span><\/h3>\n<p>\u6842\u828e\u751f\u7269\u53ef\u63d0\u4f9b\u5173\u952e\u4ea7\u54c1\u652f\u6491\uff1a<\/p>\n<p data-pm-slice=\"0 0 []\"><strong>1.\u00a0<span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\"><a href=\"https:\/\/www.guixiong.com.cn\/?page_id=1192\" target=\"_blank\" rel=\"noopener\">\u5fae\u91cfpMHC\u590d\u5408\u7269\u5408\u6210\u670d\u52a1<\/a>:\u00a0<\/span><\/strong>\u652f\u6301HLA-A*02:01\u7b4933\u79cd\u4e3b\u6d41HLA\u7b49\u4f4d\u57fa\u56e0\uff0c\u7528\u4e8e\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u9a8c\u8bc1<\/p>\n<p><strong>2\u00a0<span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\">.\u00a0<a href=\"https:\/\/www.guixiong.com.cn\/?page_id=133\" target=\"_blank\" rel=\"noopener\">pMHC\u8367\u5149\u56db\u805a\u4f53\u5408\u6210\u4ee5\u53ca\u7b5b\u9009<\/a>:\u00a0<\/span><\/strong>\u73b0\u8d27\u8986\u76d6\u591a\u79cd\u80bf\u7624\u6297\u539f\uff08\u5982HPV\/CMV\/EBV\/KRAS\u7b49\uff09\uff0c\u5feb\u901f\u5206\u9009\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de<\/p>\n<p><strong>3.\u00a0<span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\"><a href=\"https:\/\/www.guixiong.com.cn\/?page_id=546\" target=\"_blank\" rel=\"noopener\">\u5de5\u7a0b\u5316\u5448\u9012\u7ec6\u80de\u6784\u5efa<\/a>:\u00a0<\/span><\/strong>K562-HLA\u7cfb\u5217\uff0c\u6a21\u62df\u4f53\u5185\u6297\u539f\u5448\u9012\uff0c\u7528\u4e8eDC\u529f\u80fd\u6a21\u62df<\/p>\n<p><strong>4.\u00a0<span data-pm-slice=\"1 1 [&quot;para&quot;,{&quot;tagName&quot;:&quot;p&quot;,&quot;attributes&quot;:{},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;},&quot;node&quot;,{&quot;tagName&quot;:&quot;strong&quot;,&quot;attributes&quot;:{&quot;style&quot;:&quot;scrollbar-width: none;&quot;},&quot;namespaceURI&quot;:&quot;http:\/\/www.w3.org\/1999\/xhtml&quot;}]\"><a href=\"https:\/\/www.guixiong.com.cn\/?page_id=1489\" target=\"_blank\" rel=\"noopener\">\u5355\u514b\u9686TCR\u6d4b\u5e8f<\/a>:\u00a0<\/span><\/strong>\u4ece\u56db\u805a\u4f53\u9633\u6027T\u7ec6\u80de\u4e2d\u83b7\u53d6\u914d\u5bf9\u94fe\u7684TCR\u4e3b\u514b\u9686<\/p>\n<p><strong>5.\u00a0<span data-pm-slice=\"1 1 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6<\/p>","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u63ed\u793a\uff0c\u4e00\u4e2a\u540d\u4e3aV2\u7684T\u7ec6\u80de\u6a21\u62df\u6297\u4f53\uff08TCRm\uff09\uff0c\u901a\u8fc7\u5f62\u6210\u4e00\u4e2a\u7531\u758f\u6c34\u6c28\u57fa\u9178\u6784\u6210\u7684\u201c\u7b3c\u5b50\u201d\uff0c\u7cbe\u51c6\u6355\u83b7\u5e76\u8bc6\u522bKR&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"default","_kad_post_title":"default","_kad_post_layout":"default","_kad_post_sidebar_id":"","_kad_post_content_style":"default","_kad_post_vertical_padding":"default","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"class_list":["post-1674","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/1674","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1674"}],"version-history":[{"count":2,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/1674\/revisions"}],"predecessor-version":[{"id":1679,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/1674\/revisions\/1679"}],"wp:attachment":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}