{"id":782,"date":"2025-07-09T04:20:36","date_gmt":"2025-07-09T04:20:36","guid":{"rendered":"http:\/\/60.204.213.123\/?page_id=782"},"modified":"2026-01-23T08:55:05","modified_gmt":"2026-01-23T08:55:05","slug":"mart1-27-35-hla-a0201-10","status":"publish","type":"page","link":"https:\/\/www.guixiong.com.cn\/?page_id=782","title":{"rendered":"ESAT-6 (82-90) HLA-A*02:01"},"content":{"rendered":"\r\n

\u9776\u70b9\u8bf4\u660e<\/h3>\r\n\r\n\r\n\r\n

ESAT-6 (82-90) \u662f6 kDa early secretory antigenic target ESXA\u86cb\u767d\u7684\u80bd\u6bb5AMASTEGNV\uff0c\u7269\u79cd\u662fMycobacterium tuberculosis H37Rv\u3002<\/p>\r\n\r\n\r\n\r\n

AMASTEGNV\u662f\u4e00\u79cd\u7ebf\u6027\u80bd\u8868\u4f4d\uff08\u8868\u4f4dID 3064\uff09\uff0c\u662f\u7ed3\u6838\u5206\u679d\u6746\u83cc\u4e2d\u7814\u7a76\u76846 kDa\u65e9\u671f\u5206\u6ccc\u6297\u539f\u9776\u70b9\u7684\u4e00\u90e8\u5206\uff08UniProt\uff1aP9WNK7\uff09\u3002<\/p>\r\n\r\n\r\n\r\n

 <\/p>\r\n\r\n\r\n\r\n

HLA\u7c7b\u578b<\/h3>\r\n\r\n\r\n\r\n

HLA-A*02:01\uff0c \u4e2d\u56fd\u4eba\u5206\u5e03\u9891\u738712.036%<\/a><\/p>\r\n\r\n\r\n\r\n

 <\/p>\r\n\r\n\r\n\r\n

\u6297\u539f\u548cHLA\u7684\u4eb2\u548c\u529b<\/h3>\r\n\r\n\r\n\r\n

 <\/p>\r\n\r\n\r\n\r\n

NetMHCpan 4.1<\/strong>\u00a0<\/a> \u8ba1\u7b97AMASTEGNV\u4e0eHLA-A*02:01\u4eb2\u548c\u529b\u4e3a 591.10 nM\u3002<\/p>\r\n\r\n\r\n\r\n

 <\/p>\r\n\r\n\r\n\r\n

\u4ea7\u54c1\u7c7b\u578b\u548c\u5e94\u7528<\/h3>\r\n\r\n\r\n\r\n

 <\/p>\r\n\r\n\r\n\r\n

\r\n\r\n\r\n\r\n\r\n\r\n\r\n
\u4ea7\u54c1\u7c7b\u578b<\/td>\r\n\u89c4\u683c<\/td>\r\n\u4ef7\u683c<\/td>\r\n<\/tr>\r\n
\u6d41\u5f0f\u68c0\u6d4b\u4e0e\u5206\u9009<\/td>\r\nESAT-6 (82-90) HLA-A*02:01 PE \/ APC \/ Alexa Fluor 488<\/td>\r\n7200\u5143\/50ug, 11800\u5143\/100ug<\/td>\r\n<\/tr>\r\n
\u78c1\u73e0\u5206\u9009<\/td>\r\nESAT-6 (82-90) HLA-A*02:01 \u78c1\u73e0<\/td>\r\n8200\u5143\/50ug, 12800\u5143\/100ug<\/td>\r\n<\/tr>\r\n
\u751f\u7269\u7d20\u5316\u590d\u5408\u7269<\/td>\r\nESAT-6 (82-90) HLA-A*02:01 -biotin<\/td>\r\n6800\u5143\/50ug, 11400\u5143\/100ug<\/td>\r\n<\/tr>\r\n<\/tbody>\r\n<\/table>\r\n<\/figure>\r\n\r\n\r\n\r\n
\r\n\r\n\r\n
\u9776\u70b9\u7ed3\u5408\u7684TCR\u5e8f\u5217<\/span><\/div>\r\n<\/div>\r\n\r\n\r\n\r\n

\u8bf7\u67e5\u770bIEDB\u6570\u636e\u5e93<\/a><\/p>\r\n\r\n\r\n\r\n

 <\/p>\r\n\r\n\r\n\r\n

\u76f8\u5173\u6587\u7ae0<\/h3>\r\n\r\n\r\n\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t
Reference - PMID<\/th>Reference - Journal<\/th>Reference - Date<\/th>Reference - Title<\/th>\n<\/tr>\n<\/thead>\n
9419365<\/td>Proc Natl Acad Sci U S A<\/td>1998<\/td>Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis.<\/td>\n<\/tr>\n
23555576<\/td>PLoS One<\/td>2013<\/td>A broad profile of co-dominant epitopes shapes the peripheral Mycobacterium tuberculosis specific CD8+ T-cell immune response in South African patients with active tuberculosis.<\/td>\n<\/tr>\n
25809751<\/td>Int J Infect Dis<\/td>2015<\/td>Frequency of Mycobacterium tuberculosis-specific CD8+ T-cells in the course of anti-tuberculosis treatment.<\/td>\n<\/tr>\n
25631937<\/td>Eur J Immunol<\/td>2015<\/td>Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines.<\/td>\n<\/tr>\n
25809750<\/td>Int J Infect Dis<\/td>2015<\/td>Mycobacterium tuberculosis-specific and MHC class I-restricted CD8+ T-cells exhibit a stem cell precursor-like phenotype in patients with active pulmonary tuberculosis.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\r\n\r\n\r\n

 <\/p>\r\n\r\n\r\n\r\n

 <\/p>\r\n

Views: 3<\/p>","protected":false},"excerpt":{"rendered":"

\u9776\u70b9\u8bf4\u660e ESAT-6 (82-90) \u662f6 kDa early secretory antigenic ta…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"default","_kad_post_title":"default","_kad_post_layout":"default","_kad_post_sidebar_id":"","_kad_post_content_style":"default","_kad_post_vertical_padding":"default","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"class_list":["post-782","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/782","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=782"}],"version-history":[{"count":6,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/782\/revisions"}],"predecessor-version":[{"id":1581,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/782\/revisions\/1581"}],"wp:attachment":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=782"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}