<\/p>\n\n\n\n
\u4ea7\u54c1\u7c7b\u578b\u548c\u5e94\u7528<\/h3>\n\n\n\n
<\/p>\n\n\n\n <\/p>\n\n\n\n MEVGWYRSPFSRVVHLYRNGK\u591a\u80bd\u523a\u6fc0H2-IA-a\/b \u9650\u5236\u6027PBMC\u540e\uff0c\u4f7f\u7528MGP(35-55) H2-IA-a\/b \u56db\u805a\u4f53\u548c\u6297CD4-FITC\u6297\u4f53\u68c0\u6d4b\u3002\u4e0b\u56fe\u5de6\u56fe\u4e3a\u6297\u539f\u80bdMEVGWYRSPFSRVVHLYRNGK\u523a\u6fc0\u7ec4\uff0c\u53f3\u56fe\u4e3a\u672a\u52a0\u6297\u539f\u80bd\u523a\u6fc0\u7ec4\u3002<\/p>\n\n\n\n \u8bf7\u67e5\u770bIEDB\u6570\u636e\u5e93<\/a><\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n Views: 11<\/p>","protected":false},"excerpt":{"rendered":" \u9776\u70b9\u8bf4\u660e MOG(35-55) \u6765\u81ea\u9ad3\u9798\u5c11\u7a81\u80f6\u8d28\u7ec6\u80de\u7cd6\u86cb\u767dmyelin\/oligodendrocyte gly…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"class_list":["post-916","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/916","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=916"}],"version-history":[{"count":8,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/916\/revisions"}],"predecessor-version":[{"id":1057,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/916\/revisions\/1057"}],"wp:attachment":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=916"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\u4ea7\u54c1\u7c7b\u578b<\/td> \u89c4\u683c<\/td> \u4ef7\u683c<\/td><\/tr> \u6d41\u5f0f\u68c0\u6d4b\u4e0e\u5206\u9009<\/td> MGP(35-55) H2-IA-a\/b PE \/ APC \/ Alexa Fluor 488<\/td> 7200\u5143\/50ug, 11800\u5143\/100ug<\/td><\/tr> \u78c1\u73e0\u5206\u9009<\/td> MGP(35-55) H2-IA-a\/b \u78c1\u73e0<\/td> 8200\u5143\/50ug, 12800\u5143\/100ug<\/td><\/tr> \u751f\u7269\u7d20\u5316\u590d\u5408\u7269<\/td> MGP(35-55) H2-IA-a\/b-biotin<\/td> 6800\u5143\/50ug, 11400\u5143\/100ug<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n \u5b9e\u6d4b\u7ed3\u679c<\/h3>\n\n\n\n
\u80bd\u523a\u6fc0PBMC\u540e\u68c0\u6d4b\u6297\u539f\u7279\u5f02\u6027CD4+T\u7ec6\u80de<\/h3>\n\n\n\n
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\u9776\u70b9\u7ed3\u5408\u7684TCR\u5e8f\u5217<\/h3>\n\n\n\n
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\n\t \nReceptor - IEDB Receptor ID<\/th> Chain 1 - Calculated V Gene<\/th> Chain 1 - Calculated D Gene<\/th> Chain 1 - Calculated J Gene<\/th> Chain 1 - CDR3 Curated<\/th> Chain 2 - Calculated V Gene<\/th> Chain 2 - Calculated D Gene<\/th> Chain 2 - Calculated J Gene<\/th> Chain 2 - CDR3 Curated<\/th> <\/th>\n<\/tr>\n<\/thead>\n \n\t 1805<\/td> TRAV9D-4<\/td> <\/td> <\/td> VYFCALRSYNFGF<\/td> TRBV16*04<\/td> <\/td> <\/td> ASSLDCGANP<\/td> <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n \u76f8\u5173\u6587\u7ae0<\/h3>\n\n\n\n
\n\n
\n\t \nReference - PMID<\/th> Reference - Journal<\/th> Reference - Date<\/th> Reference - Title<\/th>\n<\/tr>\n<\/thead>\n \n\t 15114658<\/td> Eur J Immunol<\/td> 2004<\/td> Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice.<\/td>\n<\/tr>\n \n\t 16785554<\/td> J Immunol<\/td> 2006<\/td> IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 12807824<\/td> Int Immunol<\/td> 2003<\/td> Protection from autoimmune brain inflammation in mice lacking IFN-regulatory factor-1 is associated with Th2-type cytokines.<\/td>\n<\/tr>\n \n\t 10626667<\/td> J Neuroimmunol<\/td> 2000<\/td> Anti-IL-12 antibody prevents the development and progression of multiple sclerosis-like relapsing--remitting demyelinating disease in NOD mice induced with myelin oligodendrocyte glycoprotein peptide.<\/td>\n<\/tr>\n \n\t 8965116<\/td> J Neurol<\/td> 1996<\/td> The autoimmune reactivity to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis is potentially pathogenic: effect of copolymer 1 on MOG-induced disease.<\/td>\n<\/tr>\n \n\t 12578856<\/td> Int Immunol<\/td> 2003<\/td> Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG-specific T cells on oligomeric MHC class I molecules.<\/td>\n<\/tr>\n \n\t 12604312<\/td> J Autoimmun<\/td> 2003<\/td> Optimization of an animal model of experimental autoimmune encephalomyelitis achieved with a multiple MOG(35-55)peptide in C57BL6\/J strain of mice.<\/td>\n<\/tr>\n \n\t 16341241<\/td> Nat Med<\/td> 2006<\/td> Lipid microarrays identify key mediators of autoimmune brain inflammation.<\/td>\n<\/tr>\n \n\t 10441162<\/td> J Autoimmun<\/td> 1999<\/td> Effect of the bm12 class II mutation on proliferative and cytokine responses of encephalitogenic T cells in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 18209046<\/td> J Immunol<\/td> 2008<\/td> In trans T cell tolerance diminishes autoantibody responses and exacerbates experimental allergic encephalomyelitis.<\/td>\n<\/tr>\n \n\t 18354166<\/td> J Immunol<\/td> 2008<\/td> Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen.<\/td>\n<\/tr>\n \n\t 18684939<\/td> J Immunol<\/td> 2008<\/td> CD11c+CD11b+ dendritic cells play an important role in intravenous tolerance and the suppression of experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 18582952<\/td> J Neuroimmunol<\/td> 2008<\/td> Behavioral and pathological outcomes in MOG 35-55 experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 18566399<\/td> J Immunol<\/td> 2008<\/td> Lithium prevents and ameliorates experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 18981103<\/td> J Immunol<\/td> 2008<\/td> MHC variant peptide-mediated anergy of encephalitogenic T cells requires SHP-1.<\/td>\n<\/tr>\n \n\t 19402218<\/td> Neuroreport<\/td> 2009<\/td> Selective phosphodiesterase-3 inhibitor cilostazol ameliorates experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 19443805<\/td> Stroke<\/td> 2009<\/td> Recombinant T cell receptor ligand treats experimental stroke.<\/td>\n<\/tr>\n \n\t 19299745<\/td> J Immunol<\/td> 2009<\/td> Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity.<\/td>\n<\/tr>\n \n\t 12616486<\/td> Eur J Immunol<\/td> 2003<\/td> Heterozygous null mutation of myelin P0 protein enhances susceptibility to autoimmune neuritis targeting P0 peptide.<\/td>\n<\/tr>\n \n\t 18349128<\/td> Am J Pathol<\/td> 2008<\/td> Antigen-induced Pten gene deletion in T cells exacerbates neuropathology in experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 18577591<\/td> Proc Natl Acad Sci U S A<\/td> 2008<\/td> IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 18490725<\/td> J Immunol<\/td> 2008<\/td> Induction of anergy by antibody blockade of TCR in myelin oligodendrocyte glycoprotein-specific cells.<\/td>\n<\/tr>\n \n\t 17911594<\/td> J Immunol<\/td> 2007<\/td> CD8 T cell responses to myelin oligodendrocyte glycoprotein-derived peptides in humanized HLA-A*0201-transgenic mice.<\/td>\n<\/tr>\n \n\t 17384649<\/td> Nat Med<\/td> 2007<\/td> Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.<\/td>\n<\/tr>\n \n\t 17207459<\/td> Biochem Biophys Res Commun<\/td> 2007<\/td> A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis.<\/td>\n<\/tr>\n \n\t 17964666<\/td> J Neuroimmunol<\/td> 2007<\/td> Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency.<\/td>\n<\/tr>\n \n\t 17202353<\/td> J Immunol<\/td> 2007<\/td> Involvement of regulatory T cells in the experimental autoimmune encephalomyelitis-preventive effect of dendritic cells expressing myelin oligodendrocyte glycoprotein plus TRAIL.<\/td>\n<\/tr>\n \n\t 16990050<\/td> Clin Immunol<\/td> 2007<\/td> Altered susceptibility to EAE in congenic NOD mice: Altered processing of the encephalitogenic MOG35-55 peptide by NOR\/LtJ mice.<\/td>\n<\/tr>\n \n\t 15699115<\/td> J Immunol<\/td> 2005<\/td> Prevention of experimental autoimmune encephalomyelitis by transfer of embryonic stem cell-derived dendritic cells expressing myelin oligodendrocyte glycoprotein peptide along with TRAIL or programmed death-1 ligand.<\/td>\n<\/tr>\n \n\t 16301640<\/td> J Immunol<\/td> 2005<\/td> The ICOS molecule plays a crucial role in the development of mucosal tolerance.<\/td>\n<\/tr>\n \n\t 15189735<\/td> Immunity<\/td> 2004<\/td> Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo.<\/td>\n<\/tr>\n \n\t 14624757<\/td> J Autoimmun<\/td> 2003<\/td> The magnitude and encephalogenic potential of autoimmune response to MOG is enhanced in MOG deficient mice.<\/td>\n<\/tr>\n \n\t 8943561<\/td> Int Immunol<\/td> 1996<\/td> Antibody response in Lewis rats injected with myelin oligodendrocyte glycoprotein derived peptides.<\/td>\n<\/tr>\n \n\t 17257899<\/td> Clin Immunol<\/td> 2007<\/td> Monomeric DR2\/MOG-35-55 recombinant TCR ligand treats relapses of experimental encephalomyelitis in DR2 transgenic mice.<\/td>\n<\/tr>\n \n\t 16423348<\/td> Exp Neurol<\/td> 2006<\/td> Amelioration of autoimmune neuroinflammation by recombinant human alpha-fetoprotein.<\/td>\n<\/tr>\n \n\t 15593305<\/td> Eur J Immunol<\/td> 2005<\/td> Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 15728477<\/td> J Immunol<\/td> 2005<\/td> Differential effects of IL-21 during initiation and progression of autoimmunity against neuroantigen.<\/td>\n<\/tr>\n \n\t 15682385<\/td> J Neurosci Res<\/td> 2005<\/td> Anti-IL-16 therapy reduces CD4+ T-cell infiltration and improves paralysis and histopathology of relapsing EAE.<\/td>\n<\/tr>\n \n\t 15236747<\/td> J Autoimmun<\/td> 2004<\/td> Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies.<\/td>\n<\/tr>\n \n\t 14768043<\/td> Eur J Immunol<\/td> 2004<\/td> An MHC anchor-substituted analog of myelin oligodendrocyte glycoprotein 35-55 induces IFN-gamma and autoantibodies in the absence of experimental autoimmune encephalomyelitis and optic neuritis.<\/td>\n<\/tr>\n \n\t 12816990<\/td> J Immunol<\/td> 2003<\/td> Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice.<\/td>\n<\/tr>\n \n\t 12620641<\/td> J Neuroimmunol<\/td> 2003<\/td> Distinct immune regulation of the response to H-2b restricted epitope of MOG causes relapsing-remitting EAE in H-2b\/s mice.<\/td>\n<\/tr>\n \n\t 12817031<\/td> J Immunol<\/td> 2003<\/td> Rat and human myelin oligodendrocyte glycoproteins induce experimental autoimmune encephalomyelitis by different mechanisms in C57BL\/6 mice.<\/td>\n<\/tr>\n \n\t 12391178<\/td> J Immunol<\/td> 2002<\/td> Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 11869358<\/td> Immunol Cell Biol<\/td> 2002<\/td> Experimental autoimmune encephalomyelitis induction in naive mice by dendritic cells presenting a self-peptide.<\/td>\n<\/tr>\n \n\t 12811843<\/td> Eur J Immunol<\/td> 2003<\/td> Activation of invariant NKT cells by alphaGalCer administration protects mice from MOG35-55-induced EAE: critical roles for administration route and IFN-gamma.<\/td>\n<\/tr>\n \n\t 12417441<\/td> J Neuroimmunol<\/td> 2002<\/td> Induction of autoimmune encephalomyelitis and uveitis in B6 and (B6 x SJL) mice by peptides derived from myelin\/oligodendrocyte glycoprotein.<\/td>\n<\/tr>\n \n\t 11390514<\/td> J Immunol<\/td> 2001<\/td> Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL\/6 mice.<\/td>\n<\/tr>\n \n\t 9973531<\/td> Cell Immunol<\/td> 1999<\/td> IgG subclass switching is associated with the severity of experimental autoimmune encephalomyelitis induced with myelin oligodendrocyte glycoprotein peptide in NOD mice.<\/td>\n<\/tr>\n \n\t 10556797<\/td> Eur J Immunol<\/td> 1999<\/td> B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide.<\/td>\n<\/tr>\n \n\t 10477557<\/td> J Exp Med<\/td> 1999<\/td> Studies in B7-deficient mice reveal a critical role for B7 costimulation in both induction and effector phases of experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 10602017<\/td> Eur J Immunol<\/td> 1999<\/td> Decreased severity of myelin oligodendrocyte glycoprotein peptide 33 - 35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain gene.<\/td>\n<\/tr>\n \n\t 10464178<\/td> Int Immunol<\/td> 1999<\/td> Genetic susceptibility or resistance to autoimmune encephalomyelitis in MHC congenic mice is associated with differential production of pro- and anti-inflammatory cytokines.<\/td>\n<\/tr>\n \n\t 9670859<\/td> J Neuroimmunol<\/td> 1998<\/td> Acute and relapsing experimental autoimmune encephalomyelitis in IL-4- and alpha\/beta T cell-deficient C57BL\/6 mice.<\/td>\n<\/tr>\n \n\t 9794370<\/td> J Immunol<\/td> 1998<\/td> B-cell-deficient mice develop experimental allergic encephalomyelitis with demyelination after myelin oligodendrocyte glycoprotein sensitization.<\/td>\n<\/tr>\n \n\t 9771980<\/td> Autoimmunity<\/td> 1998<\/td> Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein.<\/td>\n<\/tr>\n \n\t 9362528<\/td> J Exp Med<\/td> 1997<\/td> Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells.<\/td>\n<\/tr>\n \n\t 8898962<\/td> Eur J Immunol<\/td> 1996<\/td> Delineation of the minimal encephalitogenic epitope within the immunodominant region of myelin oligodendrocyte glycoprotein: diverse V beta gene usage by T cells recognizing the core epitope encephalitogenic for T cell receptor V beta b and T cell receptor V beta a H-2b mice.<\/td>\n<\/tr>\n \n\t 8752946<\/td> J Immunol<\/td> 1996<\/td> Analysis of the fine B cell specificity during the chronic\/relapsing course of a multiple sclerosis-like disease in Lewis rats injected with the encephalitogenic myelin oligodendrocyte glycoprotein peptide 35-55.<\/td>\n<\/tr>\n \n\t 17404272<\/td> J Immunol<\/td> 2007<\/td> Interdependency of MHC class II\/self-peptide and CD1d\/self-glycolipid presentation by TNF-matured dendritic cells for protection from autoimmunity.<\/td>\n<\/tr>\n \n\t 11485734<\/td> Immunity<\/td> 2001<\/td> Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway.<\/td>\n<\/tr>\n \n\t 15372502<\/td> J Neurosci Res<\/td> 2004<\/td> HLA-DRB1*1501 risk association in multiple sclerosis may not be related to presentation of myelin epitopes.<\/td>\n<\/tr>\n \n\t 15093551<\/td> Clin Immunol<\/td> 2004<\/td> A novel retroviral gene therapy approach to inhibit specific antibody production and suppress experimental autoimmune encephalomyelitis induced by MOG and MBP.<\/td>\n<\/tr>\n \n\t 11937578<\/td> J Immunol<\/td> 2002<\/td> De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 16951350<\/td> J Immunol<\/td> 2006<\/td> Recombinant HLA-DP2 binds beryllium and tolerizes beryllium-specific pathogenic CD4+ T cells.<\/td>\n<\/tr>\n \n\t 19700760<\/td> Am J Pathol<\/td> 2009<\/td> Carcinoembryonic antigen-related cell adhesion molecule 1 modulates experimental autoimmune encephalomyelitis via an iNKT cell-dependent mechanism.<\/td>\n<\/tr>\n \n\t 19625643<\/td> J Immunol<\/td> 2009<\/td> CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells.<\/td>\n<\/tr>\n \n\t 19540601<\/td> J Neuroimmunol<\/td> 2009<\/td> Pathogenic MOG-reactive CD8+ T cells require MOG-reactive CD4+ T cells for sustained CNS inflammation during chronic EAE.<\/td>\n<\/tr>\n \n\t 19286483<\/td> Int Immunopharmacol<\/td> 2009<\/td> Decreased inflammation and augmented expression of trophic factors correlate with MOG-induced neuroprotection of the injured nigrostriatal system in the murine MPTP model of Parkinson's disease.<\/td>\n<\/tr>\n \n\t 19535153<\/td> J Neuroimmunol<\/td> 2009<\/td> Mice deficient for CCR6 fail to control chronic experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 8557821<\/td> J Neuroimmunol<\/td> 1995<\/td> The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat.<\/td>\n<\/tr>\n \n\t 19949074<\/td> J Immunol<\/td> 2010<\/td> IL-10 mediates resistance to adoptive transfer experimental autoimmune encephalomyelitis in MyD88(-\/-) mice.<\/td>\n<\/tr>\n \n\t 19201476<\/td> Mol Immunol<\/td> 2009<\/td> Transient decomplementation of mice delays onset of experimental autoimmune encephalomyelitis and impairs MOG-specific T cell response and autoantibody production.<\/td>\n<\/tr>\n \n\t 19688809<\/td> J Gene Med<\/td> 2009<\/td> FK506 as an adjuvant of tolerogenic DNA vaccination for the prevention of experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 19795414<\/td> Eur J Immunol<\/td> 2009<\/td> Haptoglobin deficiency facilitates the development of autoimmune inflammation.<\/td>\n<\/tr>\n \n\t 20147531<\/td> J Neurosci<\/td> 2010<\/td> CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis.<\/td>\n<\/tr>\n \n\t 19879259<\/td> Exp Neurol<\/td> 2010<\/td> B cells from glatiramer acetate-treated mice suppress experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 20070942<\/td> Exp Neurol<\/td> 2010<\/td> Aggravated experimental autoimmune encephalomyelitis in IL-15 knockout mice.<\/td>\n<\/tr>\n \n\t 20038601<\/td> J Exp Med<\/td> 2010<\/td> Negative regulation of autoimmune demyelination by the inhibitory receptor CLM-1.<\/td>\n<\/tr>\n \n\t 20164413<\/td> J Immunol<\/td> 2010<\/td> Contribution of myelin autoantigen citrullination to T cell autoaggression in the central nervous system.<\/td>\n<\/tr>\n \n\t 19912648<\/td> J Neuroinflammation<\/td> 2009<\/td> Modulation of experimental autoimmune encephalomyelitis by endogenous annexin A1.<\/td>\n<\/tr>\n \n\t 20167381<\/td> J Neuroimmunol<\/td> 2010<\/td> Encephalitogenic T-cells increase numbers of CNS T-cells regardless of antigen specificity by both increasing T-cell entry and preventing egress.<\/td>\n<\/tr>\n \n\t 20077431<\/td> J Neurosci Res<\/td> 2010<\/td> Therapeutic potential of experimental autoimmune encephalomyelitis by Fasudil, a Rho kinase inhibitor.<\/td>\n<\/tr>\n \n\t 19789980<\/td> J Neuroimmune Pharmacol<\/td> 2010<\/td> Recombinant TCR ligand reverses clinical signs and CNS damage of EAE induced by recombinant human MOG.<\/td>\n<\/tr>\n \n\t 20133787<\/td> Proc Natl Acad Sci U S A<\/td> 2010<\/td> Analysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab')2.<\/td>\n<\/tr>\n \n\t 20483764<\/td> J Immunol<\/td> 2010<\/td> TGF-beta-induced myelin peptide-specific regulatory T cells mediate antigen-specific suppression of induction of experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 20091246<\/td> J Neuroimmune Pharmacol<\/td> 2010<\/td> S-nitrosoglutathione a physiologic nitric oxide carrier attenuates experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 20546938<\/td> J Neuroimmunol<\/td> 2010<\/td> Antigen-specific therapy of EAE via intranasal delivery of filamentous phage displaying a myelin immunodominant epitope.<\/td>\n<\/tr>\n \n\t 20663571<\/td> J Neuroimmunol<\/td> 2010<\/td> A Lecinoxoid, an oxidized phospholipid small molecule, constrains CNS autoimmune disease.<\/td>\n<\/tr>\n \n\t 20624940<\/td> J Immunol<\/td> 2010<\/td> Regulatory B cells (B10 cells) and regulatory T cells have independent roles in controlling experimental autoimmune encephalomyelitis initiation and late-phase immunopathogenesis.<\/td>\n<\/tr>\n \n\t 20546940<\/td> J Neuroimmunol<\/td> 2010<\/td> Binding of recombinant T cell receptor ligands (RTL) to antigen presenting cells prevents upregulation of CD11b and inhibits T cell activation and transfer of experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 20641064<\/td> Ann Neurol<\/td> 2010<\/td> B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity.<\/td>\n<\/tr>\n \n\t 20857508<\/td> J Neurosci Res<\/td> 2010<\/td> Accumulation of protein carbonyls within cerebellar astrocytes in murine experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 21078910<\/td> J Immunol<\/td> 2010<\/td> Leptin modulates the survival of autoreactive CD4+ T cells through the nutrient\/energy-sensing mammalian target of rapamycin signaling pathway.<\/td>\n<\/tr>\n \n\t 20172692<\/td> J Autoimmun<\/td> 2010<\/td> Immune regulatory CNS-reactive CD8+T cells in experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 20933475<\/td> Clin Immunol<\/td> 2010<\/td> The clinical course of EAE is reflected by the dynamics of the neuroantigen-specific T cell compartment in the blood.<\/td>\n<\/tr>\n \n\t 21209700<\/td> PLoS One<\/td> 2010<\/td> Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 21273399<\/td> Int Immunol<\/td> 2011<\/td> Antigen-specific splenic CD4+ and CD8+ regulatory T cells generated via the eye, suppress experimental autoimmune encephalomyelitis either at the priming or at the effector phase.<\/td>\n<\/tr>\n \n\t 21289301<\/td> J Immunol<\/td> 2011<\/td> Coronin 1-mediated naive T cell survival is essential for the development of autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 21220453<\/td> J Exp Med<\/td> 2011<\/td> High prevalence of low affinity peptide-MHC II tetramer-negative effectors during polyclonal CD4+ T cell responses.<\/td>\n<\/tr>\n \n\t 21469129<\/td> Eur J Immunol<\/td> 2011<\/td> TCR-like antibodies distinguish conformational and 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