<\/p>\n\n\n\n
\u4ea7\u54c1\u7c7b\u578b\u548c\u5e94\u7528<\/h3>\n\n\n\n
<\/p>\n\n\n\n <\/p>\n\n\n\n SIINFEKL\u591a\u80bd\u523a\u6fc0H2Kb \u9650\u5236\u6027PBMC\u540e\uff0c\u4f7f\u7528OVA (258-265) H2Kb \u56db\u805a\u4f53\u548c\u6297CD8-FITC\u6297\u4f53\u68c0\u6d4b\u3002\u4e0b\u56fe\u5de6\u56fe\u4e3a\u6297\u539f\u80bdSIINFEKL\u523a\u6fc0\u7ec4\uff0c\u53f3\u56fe\u4e3a\u672a\u52a0\u6297\u539f\u80bd\u523a\u6fc0\u7ec4\u3002<\/p>\n\n\n\n \u8bf7\u67e5\u770bIEDB\u6570\u636e\u5e93<\/a><\/p>\n\n\n\n <\/p>\n\n\n\n <\/p>\n Views: 92<\/p>","protected":false},"excerpt":{"rendered":" \u9776\u70b9\u8bf4\u660e OVA (258-265)\u591a\u80bdSIINFEKL\u4e0eH2Kb\u5f62\u6210\u7684\u590d\u5408\u7269\uff0c\u662f\u6297\u539f\u7279\u5f02\u6027T\u7ec6\u80de\u514d\u75ab\u7684\u7ecf\u5178\u6a21…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_kadence_starter_templates_imported_post":false,"_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"class_list":["post-922","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/922","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=922"}],"version-history":[{"count":8,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/922\/revisions"}],"predecessor-version":[{"id":1058,"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=\/wp\/v2\/pages\/922\/revisions\/1058"}],"wp:attachment":[{"href":"https:\/\/www.guixiong.com.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=922"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\u4ea7\u54c1\u7c7b\u578b<\/td> \u89c4\u683c<\/td> \u4ef7\u683c<\/td><\/tr> \u6d41\u5f0f\u68c0\u6d4b\u4e0e\u5206\u9009<\/td> OVA (258-265)H2Kb PE \/ APC \/ Alexa Fluor 488<\/td> 7200\u5143\/50ug, 11800\u5143\/100ug<\/td><\/tr> \u78c1\u73e0\u5206\u9009<\/td> OVA (258-265)H2Kb\u78c1\u73e0<\/td> 8200\u5143\/50ug, 12800\u5143\/100ug<\/td><\/tr> \u751f\u7269\u7d20\u5316\u590d\u5408\u7269<\/td> OVA (258-265)H2Kb -biotin<\/td> 6800\u5143\/50ug, 11400\u5143\/100ug<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n \u5b9e\u6d4b\u7ed3\u679c<\/h3>\n\n\n\n
\u80bd\u523a\u6fc0PBMC\u540e\u68c0\u6d4b\u6297\u539f\u7279\u5f02\u6027CD8+T\u7ec6\u80de<\/h3>\n\n\n\n
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\u9776\u70b9\u7ed3\u5408\u7684TCR\u5e8f\u5217<\/h3>\n\n\n\n
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\n\t \nReceptor - IEDB Receptor ID<\/th> Chain 1 - CDR3 Curated<\/th> Chain 2 - CDR3 Curated<\/th> <\/th>\n<\/tr>\n<\/thead>\n \n\t 28799<\/td> DNYQLIWGSGTKLIIKPD<\/td> RANYEQYFGPGTRLTVL<\/td> <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n \u76f8\u5173\u6587\u7ae0<\/h3>\n\n\n\n
\n\n
\n\t \nReference - PMID<\/th> Reference - Journal<\/th> Reference - Date<\/th> Reference - Title<\/th>\n<\/tr>\n<\/thead>\n \n\t 15494519<\/td> J Immunol<\/td> 2004<\/td> Duration of infection and antigen display have minimal influence on the kinetics of the CD4+ T cell response to Listeria monocytogenes infection.<\/td>\n<\/tr>\n \n\t 15379861<\/td> Scand J Immunol<\/td> 2004<\/td> Bystander help within a polyepitope DNA vaccine improves immune responses to influenza antigens.<\/td>\n<\/tr>\n \n\t 14595439<\/td> Nat Immunol<\/td> 2003<\/td> Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).<\/td>\n<\/tr>\n \n\t 11466344<\/td> J Immunol<\/td> 2001<\/td> Multiple paths for activation of naive CD8+ T cells: CD4-independent help.<\/td>\n<\/tr>\n \n\t 9469429<\/td> J Immunol<\/td> 1998<\/td> Delivery of multiple CD8 cytotoxic T cell epitopes by DNA vaccination.<\/td>\n<\/tr>\n \n\t 8955206<\/td> J Immunol<\/td> 1996<\/td> Immunodominance analysis of CTL responses to influenza PR8 virus reveals two new dominant and subdominant Kb-restricted epitopes.<\/td>\n<\/tr>\n \n\t 10570269<\/td> J Immunol<\/td> 1999<\/td> Distinct proteolytic processes generate the C and N termini of MHC class I-binding peptides.<\/td>\n<\/tr>\n \n\t <\/td> <\/td> 2006<\/td> <\/td>\n<\/tr>\n \n\t 15489266<\/td> Proc Natl Acad Sci U S A<\/td> 2004<\/td> A totally synthetic vaccine of generic structure that targets Toll-like receptor 2 on dendritic cells and promotes antibody or cytotoxic T cell responses.<\/td>\n<\/tr>\n \n\t <\/td> <\/td> 2006<\/td> <\/td>\n<\/tr>\n \n\t 14741703<\/td> Biochem Biophys Res Commun<\/td> 2004<\/td> HCV core protein-expressing DNA vaccine induces a strong class I-binding peptide DTH response in mice.<\/td>\n<\/tr>\n \n\t 16709853<\/td> J Immunol<\/td> 2006<\/td> Epitopes derived by incidental translational frameshifting give rise to a protective CTL response.<\/td>\n<\/tr>\n \n\t 16552058<\/td> Infect Immun<\/td> 2006<\/td> Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria.<\/td>\n<\/tr>\n \n\t 14978103<\/td> J Immunol<\/td> 2004<\/td> A peptide that antagonizes TCR-mediated reactions with both syngeneic and allogeneic agonists: functional and structural aspects.<\/td>\n<\/tr>\n \n\t 11581168<\/td> Int Immunol<\/td> 2001<\/td> Generation of cytotoxic T lymphocytes by MHC class I ligands fused to heat shock cognate protein 70.<\/td>\n<\/tr>\n \n\t 7483809<\/td> Vaccine<\/td> 1995<\/td> Priming of class I-restricted cytotoxic T lymphocytes by vaccination with recombinant protein antigens.<\/td>\n<\/tr>\n \n\t 12538696<\/td> J Immunol<\/td> 2003<\/td> Mimicry of native peptide antigens by the corresponding retro-inverso analogs is dependent on their intrinsic structure and interaction propensities.<\/td>\n<\/tr>\n \n\t 15814688<\/td> J Immunol<\/td> 2005<\/td> Translation from cryptic reading frames of DNA vaccines generates an extended repertoire of immunogenic, MHC class I-restricted epitopes.<\/td>\n<\/tr>\n \n\t 17072910<\/td> Eur J Immunol<\/td> 2006<\/td> A correlation between function and selected measures of T cell avidity in influenza virus-specific CD8+ T cell responses.<\/td>\n<\/tr>\n \n\t 12406194<\/td> Parasite Immunol<\/td> 2002<\/td> Paraflagellar rod protein-specific CD8+ cytotoxic T lymphocytes target Trypanosoma cruzi-infected host cells.<\/td>\n<\/tr>\n \n\t 9418131<\/td> Int Immunol<\/td> 1997<\/td> The critical role of a solvent-exposed residue of an MHC class I-restricted peptide in MHC-peptide binding.<\/td>\n<\/tr>\n \n\t 8393442<\/td> J Biol Chem<\/td> 1993<\/td> Direct detection of major histocompatibility complex class I binding to antigenic peptides using surface plasmon resonance. Peptide immobilization and characterization of binding specificity.<\/td>\n<\/tr>\n \n\t 16731943<\/td> J Virol<\/td> 2006<\/td> Cellular and molecular requirements for association of the murine cytomegalovirus protein m4\/gp34 with major histocompatibility complex class I molecules.<\/td>\n<\/tr>\n \n\t 15925833<\/td> Clin Immunol<\/td> 2005<\/td> A soluble divalent class I MHC\/IgG1 fusion protein activates CD8+ T cells in vivo.<\/td>\n<\/tr>\n \n\t 8335903<\/td> J Immunol<\/td> 1993<\/td> Structural complexity of antigenic determinants for class I MHC-restricted, hapten-specific T cells. Two qualitatively differing types of H-2Kb-restricted TNP epitopes.<\/td>\n<\/tr>\n \n\t 12631250<\/td> Exp Dermatol<\/td> 2003<\/td> A high frequency of allergen-specific CD8+ Tc1 cells is associated with the murine immune response to the contact sensitizer trinitrophenyl.<\/td>\n<\/tr>\n \n\t 12663770<\/td> J Virol<\/td> 2003<\/td> Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL\/6 mice.<\/td>\n<\/tr>\n \n\t 10671225<\/td> Eur J Immunol<\/td> 2000<\/td> Effect of pre-existing cytotoxic T lymphocytes on therapeutic vaccines.<\/td>\n<\/tr>\n \n\t 17709425<\/td> J Exp Med<\/td> 2007<\/td> Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccination.<\/td>\n<\/tr>\n \n\t 9531271<\/td> J Immunol<\/td> 1998<\/td> Superdominance among immunodominant H-2Kb-restricted epitopes and reversal by dendritic cell-mediated antigen delivery.<\/td>\n<\/tr>\n \n\t 11180106<\/td> Eur J Immunol<\/td> 2001<\/td> Identification of endogenous peptides recognized by in vivo or in vitro generated alloreactive cytotoxic T lymphocytes: distinct characteristics correlated with CD8 dependence.<\/td>\n<\/tr>\n \n\t 7519223<\/td> J Immunol Methods<\/td> 1994<\/td> Efficacy of synthetic vaccines in the induction of cytotoxic T lymphocytes. Comparison of the costimulating support provided by helper T cells and lipoamino acid.<\/td>\n<\/tr>\n \n\t 18612271<\/td> Mol Ther<\/td> 2008<\/td> The immunogenicity of adenovirus vectors limits the multispecificity of CD8 T-cell responses to vector-encoded transgenic antigens.<\/td>\n<\/tr>\n \n\t 17067310<\/td> Immunology<\/td> 2006<\/td> Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide.<\/td>\n<\/tr>\n \n\t 11290333<\/td> Immunity<\/td> 2001<\/td> The crystal structures of K(bm1) and K(bm8) reveal that subtle changes in the peptide environment impact thermostability and alloreactivity.<\/td>\n<\/tr>\n \n\t 17719490<\/td> Chem Biol<\/td> 2007<\/td> Structural engineering of pMHC reagents for T cell vaccines and diagnostics.<\/td>\n<\/tr>\n \n\t 7708669<\/td> Proc Natl Acad Sci U S A<\/td> 1995<\/td> Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove.<\/td>\n<\/tr>\n \n\t 18922097<\/td> J Infect Dis<\/td> 2008<\/td> Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes.<\/td>\n<\/tr>\n \n\t 12083519<\/td> J Mol Biol<\/td> 2002<\/td> Crystal structure of a non-canonical high affinity peptide complexed with MHC class I: a novel use of alternative anchors.<\/td>\n<\/tr>\n \n\t 12083518<\/td> J Mol Biol<\/td> 2002<\/td> Crystal structure of a non-canonical low-affinity peptide complexed with MHC class I: a new approach for vaccine design.<\/td>\n<\/tr>\n \n\t 11884537<\/td> J Virol<\/td> 2002<\/td> Capsid-specific cytotoxic T lymphocytes recognize three distinct H-2D(b)-restricted regions of the BeAn strain of Theiler's virus and exhibit different cytokine profiles.<\/td>\n<\/tr>\n \n\t 19180468<\/td> Eur J Immunol<\/td> 2009<\/td> Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4+CD25+ T cells.<\/td>\n<\/tr>\n \n\t 12874211<\/td> J Immunol<\/td> 2003<\/td> Enhanced priming of multispecific, murine CD8+ T cell responses by DNA vaccines expressing stress protein-binding polytope peptides.<\/td>\n<\/tr>\n \n\t 19541644<\/td> Proc Natl Acad Sci U S A<\/td> 2009<\/td> Cellular immune response to cryptic epitopes during therapeutic gene transfer.<\/td>\n<\/tr>\n \n\t 19428921<\/td> Vaccine<\/td> 2009<\/td> Mechanism for increased immunogenicity of vaccines that form in vivo immune complexes with the natural anti-Gal antibody.<\/td>\n<\/tr>\n \n\t 16052529<\/td> Int J Cancer<\/td> 2006<\/td> Transcutaneous immunization in mice: induction of T-helper and cytotoxic T lymphocyte responses and protection against human papillomavirus-induced tumors.<\/td>\n<\/tr>\n \n\t 1383319<\/td> J Immunol<\/td> 1992<\/td> Role of hapten-anchoring peptides in defining hapten-epitopes for MHC-restricted cytotoxic T cells. Cross-reactive TNP-determinants on different peptides.<\/td>\n<\/tr>\n \n\t 19542448<\/td> J Immunol<\/td> 2009<\/td> Elimination of immunodominant epitopes from multispecific DNA-based vaccines allows induction of CD8 T cells that have a striking antiviral potential.<\/td>\n<\/tr>\n \n\t 16038719<\/td> Thromb Res<\/td> 2005<\/td> Identification of a novel immunodominant cytotoxic T lymphocyte epitope derived from human factor VIII in a murine model of hemophilia A.<\/td>\n<\/tr>\n \n\t 9103427<\/td> J Immunol<\/td> 1997<\/td> Differential contact of disparate class I\/peptide complexes as the basis for epitope cross-recognition by a single T cell receptor.<\/td>\n<\/tr>\n \n\t 19949070<\/td> J Immunol<\/td> 2010<\/td> Absence of tapasin alters immunodominance against a lymphocytic choriomeningitis virus polytope.<\/td>\n<\/tr>\n \n\t 19949110<\/td> J Immunol<\/td> 2010<\/td> Altered CD8(+) T cell immunodominance after vaccinia virus infection and the naive repertoire in inbred and F(1) mice.<\/td>\n<\/tr>\n \n\t 15302863<\/td> J Biol Chem<\/td> 2004<\/td> Antibody specific for the peptide.major histocompatibility complex. Is it T cell receptor-like?<\/td>\n<\/tr>\n \n\t 7814870<\/td> J Immunol<\/td> 1995<\/td> The role of MHC class I molecules in the generation of endogenous peptide\/MHC complexes.<\/td>\n<\/tr>\n \n\t 7535183<\/td> Immunity<\/td> 1995<\/td> Contribution of proteasome-mediated proteolysis to the hierarchy of epitopes presented by major histocompatibility complex class I molecules.<\/td>\n<\/tr>\n \n\t 8370082<\/td> Cell Immunol<\/td> 1993<\/td> Both human and mouse cells expressing H-2Kb and ovalbumin process the same peptide, SIINFEKL.<\/td>\n<\/tr>\n \n\t 18929574<\/td> J Mol Biol<\/td> 2008<\/td> The crystal structure of CD8 in complex with YTS156.7.7 Fab and interaction with other CD8 antibodies define the binding mode of CD8 alphabeta to MHC class I.<\/td>\n<\/tr>\n \n\t 20006892<\/td> Virology<\/td> 2010<\/td> HBsAg-vectored vaccines simultaneously deliver CTL responses to protective epitopes from multiple viral pathogens.<\/td>\n<\/tr>\n \n\t 20017190<\/td> Eur J Immunol<\/td> 2010<\/td> Tapasin edits peptides on MHC class I molecules by accelerating peptide exchange.<\/td>\n<\/tr>\n \n\t 18426793<\/td> J Biol Chem<\/td> 2008<\/td> Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.<\/td>\n<\/tr>\n \n\t 20439913<\/td> J Immunol<\/td> 2010<\/td> Lack of original antigenic sin in recall CD8(+) T cell responses.<\/td>\n<\/tr>\n \n\t 20616089<\/td> Proc Natl Acad Sci U S A<\/td> 2010<\/td> Exploiting cross-priming to generate protective CD8 T-cell immunity rapidly.<\/td>\n<\/tr>\n \n\t 12407019<\/td> Int Immunol<\/td> 2002<\/td> Comparison of the frequency of peptide-specific cytotoxic T lymphocytes restricted by self- and allo-MHC following in vitro T cell priming.<\/td>\n<\/tr>\n \n\t 7947455<\/td> Int Immunol<\/td> 1994<\/td> Minor pocket B influences peptide binding, peptide presentation and alloantigenicity of H-2Kb.<\/td>\n<\/tr>\n \n\t 17114426<\/td> J Immunol<\/td> 2006<\/td> Paternal antigen-bearing cells transferred during insemination do not stimulate anti-paternal CD8+ T cells: role of estradiol in locally inhibiting CD8+ T cell responses.<\/td>\n<\/tr>\n \n\t 10477598<\/td> J Immunol<\/td> 1999<\/td> The mode of ligand recognition by two peptide:MHC class I-specific monoclonal antibodies.<\/td>\n<\/tr>\n \n\t 12845499<\/td> Immunogenetics<\/td> 2003<\/td> A single nucleotide polymorphism in the Emp3 gene defines the H4 minor histocompatibility antigen.<\/td>\n<\/tr>\n \n\t 9759870<\/td> J Immunol<\/td> 1998<\/td> The molecular and functional characterization of a dominant minor H antigen, H60.<\/td>\n<\/tr>\n \n\t 9551915<\/td> J Immunol<\/td> 1998<\/td> Degenerate recognition of alloantigenic peptides on a positive-selecting class I molecule.<\/td>\n<\/tr>\n \n\t 8906823<\/td> J Immunol<\/td> 1996<\/td> Alloreactive CD8+ T cells can recognize unusual, rare, and unique processed peptide\/MHC complexes.<\/td>\n<\/tr>\n \n\t 7539039<\/td> J Exp Med<\/td> 1995<\/td> Decrypting the structure of major histocompatibility complex class I-restricted cytotoxic T lymphocyte epitopes with complex peptide libraries.<\/td>\n<\/tr>\n \n\t 8084337<\/td> Mol Immunol<\/td> 1994<\/td> A cytotoxic T lymphocyte clone can recognize the same naturally occurring self peptide in association with a self and nonself class I MHC protein.<\/td>\n<\/tr>\n \n\t 7972089<\/td> Proc Natl Acad Sci U S A<\/td> 1994<\/td> High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins.<\/td>\n<\/tr>\n \n\t 7522161<\/td> Eur J Immunol<\/td> 1994<\/td> Major histocompatibility complex class I allele-specific peptide libraries: identification of peptides that mimic an H-Y T cell epitope.<\/td>\n<\/tr>\n \n\t 1318201<\/td> Eur J Immunol<\/td> 1992<\/td> A viral peptide can mimic an endogenous peptide for allorecognition of a major histocompatibility complex class I product.<\/td>\n<\/tr>\n \n\t 20411564<\/td> Eur J Immunol<\/td> 2010<\/td> Modulating numbers and phenotype of CD8+ T cells in secondary immune responses.<\/td>\n<\/tr>\n \n\t 21264852<\/td> Eur J Immunol<\/td> 2011<\/td> Memory precursor phenotype of CD8+ T cells reflects early antigenic experience rather than memory numbers in a model of localized acute influenza infection.<\/td>\n<\/tr>\n \n\t 21264321<\/td> PLoS One<\/td> 2010<\/td> Liposome-coupled peptides induce long-lived memory CD8 T cells without CD4 T cells.<\/td>\n<\/tr>\n \n\t 21625449<\/td> PLoS One<\/td> 2011<\/td> Theiler's murine encephalomyelitis virus as a vaccine candidate for immunotherapy.<\/td>\n<\/tr>\n \n\t 19892989<\/td> Science<\/td> 2009<\/td> A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire.<\/td>\n<\/tr>\n \n\t 21742967<\/td> J Immunol<\/td> 2011<\/td> Soluble proteins induce strong CD8+ T cell and antibody responses through electrostatic association with simple cationic or anionic lipopeptides that target TLR2.<\/td>\n<\/tr>\n \n\t 21674137<\/td> J Clin Immunol<\/td> 2011<\/td> A distinct role of CD4+ Th17- and Th17-stimulated CD8+ CTL in the pathogenesis of type 1 diabetes and experimental autoimmune encephalomyelitis.<\/td>\n<\/tr>\n \n\t 22039305<\/td> J Immunol<\/td> 2011<\/td> Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses.<\/td>\n<\/tr>\n \n\t 22403068<\/td> Proc Natl Acad Sci U S A<\/td> 2012<\/td> Promiscuous binding of extracellular peptides to cell surface class I MHC protein.<\/td>\n<\/tr>\n \n\t 9151706<\/td> J Exp Med<\/td> 1997<\/td> Altered hapten ligands antagonize trinitrophenyl-specific cytotoxic T cells and block internalization of hapten-specific receptors.<\/td>\n<\/tr>\n \n\t 22745779<\/td> PLoS One<\/td> 2012<\/td> Linear fidelity in quantification of anti-viral CD8+ T cells.<\/td>\n<\/tr>\n \n\t 22809501<\/td> Biochem Biophys Res Commun<\/td> 2012<\/td> Repetitive peptide boosting progressively enhances functional memory CTLs.<\/td>\n<\/tr>\n \n\t 22821960<\/td> J Immunol<\/td> 2012<\/td> Acquisition of MHC:peptide complexes by dendritic cells contributes to the generation of antiviral CD8+ T cell immunity in vivo.<\/td>\n<\/tr>\n \n\t 22987800<\/td> J Exp Med<\/td> 2012<\/td> Autoreactive T cells bypass negative selection and respond to self-antigen stimulation during infection.<\/td>\n<\/tr>\n \n\t 22949678<\/td> Proc Natl Acad Sci U S A<\/td> 2012<\/td> Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters.<\/td>\n<\/tr>\n \n\t 23029192<\/td> PLoS One<\/td> 2012<\/td> A polymeric protein induces specific cytotoxicity in a TLR4 dependent manner in the absence of adjuvants.<\/td>\n<\/tr>\n \n\t 23209377<\/td> PLoS Biol<\/td> 2012<\/td> Structural mechanism of ER retrieval of MHC class I by cowpox.<\/td>\n<\/tr>\n \n\t 23041566<\/td> J Immunol<\/td> 2012<\/td> SAP is required for the development of innate phenotype in H2-M3--restricted Cd8(+) T cells.<\/td>\n<\/tr>\n \n\t 23382674<\/td> PLoS Pathog<\/td> 2013<\/td> Kinetics of antigen expression and epitope presentation during virus infection.<\/td>\n<\/tr>\n \n\t 23455500<\/td> J Immunol<\/td> 2013<\/td> Competition for antigen at the level of the APC is a major determinant of immunodominance during memory inflation in murine cytomegalovirus infection.<\/td>\n<\/tr>\n \n\t 23404526<\/td> Eur J Immunol<\/td> 2013<\/td> Competition between T cells maintains clonal dominance during memory inflation induced by MCMV.<\/td>\n<\/tr>\n \n\t 23633956<\/td> PLoS Pathog<\/td> 2013<\/td> Immunodomination during peripheral vaccinia virus infection.<\/td>\n<\/tr>\n \n\t 19124736<\/td> J Immunol<\/td> 2009<\/td> Endogenous 4-1BB ligand plays a critical role in protection from influenza-induced disease.<\/td>\n<\/tr>\n \n\t 20007267<\/td> J Virol<\/td> 2010<\/td> Vaccination with an adenoviral vector that encodes and displays a retroviral antigen induces improved neutralizing antibody and CD4+ T-cell responses and confers enhanced protection.<\/td>\n<\/tr>\n \n\t 16421293<\/td> J Neurosci<\/td> 2006<\/td> Traumatic injury and the presence of antigen differentially contribute to T-cell recruitment in the CNS.<\/td>\n<\/tr>\n \n\t 20601952<\/td> Nat Immunol<\/td> 2010<\/td> T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells.<\/td>\n<\/tr>\n \n\t 18193057<\/td> Nat Med<\/td> 2008<\/td> Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses.<\/td>\n<\/tr>\n \n\t 19017950<\/td> J Immunol<\/td> 2008<\/td> The Erk2 MAPK regulates CD8 T cell proliferation and survival.<\/td>\n<\/tr>\n \n\t 21098221<\/td> J Immunol<\/td> 2011<\/td> A role for IL-15 in the migration of effector CD8 T cells to the lung airways following influenza infection.<\/td>\n<\/tr>\n \n\t 12910264<\/td> Nat Med<\/td> 2003<\/td> Bone marrow as a priming site for 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